Cheap Flights from Guatemala to Rio Negro (GT to MDE)

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US$145

6:10am - 2:00pm
Fri Apr 18th 2025

6h 50m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Fri Apr 18th 2025 Avianca · AV 655 Depart at 6:10am from Guatemala City (GUA) Fly for 1h 30m Arrive at 7:40am in San José (SJO)

Layover in San José for 3h 20m

Fri Apr 18th 2025 Avianca · AV 25 Depart at 11:00am from San José (SJO) Fly for 2h 0m Arrive at 2:00pm in Medellín (MDE)

Book Flight
US$146

4:35pm - 11:02pm
Fri Apr 18th 2025

5h 27m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Fri Apr 18th 2025 Avianca · AV 35 Depart at 4:35pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:50pm in Bogotá (BOG)

Layover in Bogotá for 1h 10m

Fri Apr 18th 2025 Avianca · AV 9242 Depart at 10:00pm from Bogotá (BOG) Fly for 1h 2m Arrive at 11:02pm in Medellín (MDE)

Book Flight
US$171

4:23pm - 6:40am
Fri Apr 18th 2025

13h 17m
Guatemala City (GUA) → Medellín (EOH)

2 Stops

Fri Apr 18th 2025 Copa Airlines · CM 361 Depart at 4:23pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50pm in Panama (PTY)

Layover in Panama for 1h 26m

Fri Apr 18th 2025 Copa Airlines · CM 876 Depart at 9:16pm from Panama (PTY) Fly for 1h 39m Arrive at 10:55pm in Bogotá (BOG)

Layover in Bogotá for 6h 35m

Sat Apr 19th 2025 Clic · VE 9104 Depart at 5:30am from Bogotá (BOG) Fly for 1h 10m Arrive at 6:40am in Medellín (EOH)

Book Flight
US$172

4:23am - 10:29am
Thu Apr 17th 2025

5h 6m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Thu Apr 17th 2025 Copa Airlines · CM 407 Depart at 4:23am from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50am in Panama (PTY)

Layover in Panama for 1h 14m

Thu Apr 17th 2025 Copa Airlines · CM 855 Depart at 9:04am from Panama (PTY) Fly for 1h 25m Arrive at 10:29am in Medellín (MDE)

Book Flight
US$172

4:23am - 10:29am
Fri Apr 18th 2025

5h 6m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Fri Apr 18th 2025 Copa Airlines · CM 407 Depart at 4:23am from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50am in Panama (PTY)

Layover in Panama for 1h 14m

Fri Apr 18th 2025 Copa Airlines · CM 855 Depart at 9:04am from Panama (PTY) Fly for 1h 25m Arrive at 10:29am in Medellín (MDE)

Book Flight
US$172

4:23pm - 10:52pm
Thu Apr 17th 2025

5h 29m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Thu Apr 17th 2025 Copa Airlines · CM 361 Depart at 4:23pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50pm in Panama (PTY)

Layover in Panama for 1h 37m

Thu Apr 17th 2025 Copa Airlines · CM 155 Depart at 9:27pm from Panama (PTY) Fly for 1h 25m Arrive at 10:52pm in Medellín (MDE)

Book Flight
US$172

10:23am - 5:01pm
Wed Apr 16th 2025

5h 38m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Copa Airlines · CM 111 Depart at 10:23am from Guatemala City (GUA) Fly for 2h 26m Arrive at 1:49pm in Panama (PTY)

Layover in Panama for 1h 47m

Wed Apr 16th 2025 Copa Airlines · CM 156 Depart at 3:36pm from Panama (PTY) Fly for 1h 25m Arrive at 5:01pm in Medellín (MDE)

Book Flight
US$172

10:23am - 5:01pm
Thu Apr 17th 2025

5h 38m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Thu Apr 17th 2025 Copa Airlines · CM 111 Depart at 10:23am from Guatemala City (GUA) Fly for 2h 26m Arrive at 1:49pm in Panama (PTY)

Layover in Panama for 1h 47m

Thu Apr 17th 2025 Copa Airlines · CM 156 Depart at 3:36pm from Panama (PTY) Fly for 1h 25m Arrive at 5:01pm in Medellín (MDE)

Book Flight
US$172

1:12pm - 8:14pm
Wed Apr 16th 2025

6h 2m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Copa Airlines · CM 384 Depart at 1:12pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 4:39pm in Panama (PTY)

Layover in Panama for 2h 10m

Wed Apr 16th 2025 Copa Airlines · CM 163 Depart at 6:49pm from Panama (PTY) Fly for 1h 25m Arrive at 8:14pm in Medellín (MDE)

Book Flight
US$172

7:09am - 2:15pm
Wed Apr 16th 2025

6h 6m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Copa Airlines · CM 389 Depart at 7:09am from Guatemala City (GUA) Fly for 2h 27m Arrive at 10:36am in Panama (PTY)

Layover in Panama for 2h 14m

Wed Apr 16th 2025 Copa Airlines · CM 502 Depart at 12:50pm from Panama (PTY) Fly for 1h 25m Arrive at 2:15pm in Medellín (MDE)

Book Flight
US$172

7:09am - 2:15pm
Thu Apr 17th 2025

6h 6m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Thu Apr 17th 2025 Copa Airlines · CM 389 Depart at 7:09am from Guatemala City (GUA) Fly for 2h 27m Arrive at 10:36am in Panama (PTY)

Layover in Panama for 2h 14m

Thu Apr 17th 2025 Copa Airlines · CM 502 Depart at 12:50pm from Panama (PTY) Fly for 1h 25m Arrive at 2:15pm in Medellín (MDE)

Book Flight
US$174

10:23am - 7:58pm
Wed Apr 16th 2025

8h 35m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Copa Airlines · CM 111 Depart at 10:23am from Guatemala City (GUA) Fly for 2h 26m Arrive at 1:49pm in Panama (PTY)

Layover in Panama for 4h 44m

Wed Apr 16th 2025 Copa Airlines · CM 208 Depart at 6:33pm from Panama (PTY) Fly for 1h 25m Arrive at 7:58pm in Medellín (MDE)

Book Flight
US$174

10:23am - 8:14pm
Wed Apr 16th 2025

8h 51m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Copa Airlines · CM 111 Depart at 10:23am from Guatemala City (GUA) Fly for 2h 26m Arrive at 1:49pm in Panama (PTY)

Layover in Panama for 5h 0m

Wed Apr 16th 2025 Copa Airlines · CM 163 Depart at 6:49pm from Panama (PTY) Fly for 1h 25m Arrive at 8:14pm in Medellín (MDE)

Book Flight
US$174

7:09am - 5:01pm
Wed Apr 16th 2025

8h 52m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Copa Airlines · CM 389 Depart at 7:09am from Guatemala City (GUA) Fly for 2h 27m Arrive at 10:36am in Panama (PTY)

Layover in Panama for 5h 0m

Wed Apr 16th 2025 Copa Airlines · CM 156 Depart at 3:36pm from Panama (PTY) Fly for 1h 25m Arrive at 5:01pm in Medellín (MDE)

Book Flight
US$174

4:23pm - 8:18am
Wed Apr 16th 2025

14h 55m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Copa Airlines · CM 361 Depart at 4:23pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50pm in Panama (PTY)

Layover in Panama for 11h 3m

Thu Apr 17th 2025 Copa Airlines · CM 150 Depart at 6:53am from Panama (PTY) Fly for 1h 25m Arrive at 8:18am in Medellín (MDE)

Book Flight
US$178

4:23am - 3:40pm
Fri Apr 18th 2025

10h 17m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Fri Apr 18th 2025 Copa Airlines · CM 407 Depart at 4:23am from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50am in Panama (PTY)

Layover in Panama for 1h 37m

Fri Apr 18th 2025 Copa Airlines · CM 332 Depart at 9:27am from Panama (PTY) Fly for 1h 39m Arrive at 11:06am in Bogotá (BOG)

Layover in Bogotá for 3h 32m

Fri Apr 18th 2025 Wingo airlines · P5 7272 Depart at 2:38pm from Bogotá (BOG) Fly for 1h 2m Arrive at 3:40pm in Medellín (MDE)

Book Flight
US$178

10:23am - 11:11pm
Thu Apr 17th 2025

11h 48m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Thu Apr 17th 2025 Copa Airlines · CM 111 Depart at 10:23am from Guatemala City (GUA) Fly for 2h 26m Arrive at 1:49pm in Panama (PTY)

Layover in Panama for 1h 39m

Thu Apr 17th 2025 Copa Airlines · CM 413 Depart at 3:28pm from Panama (PTY) Fly for 1h 39m Arrive at 5:07pm in Bogotá (BOG)

Layover in Bogotá for 5h 2m

Thu Apr 17th 2025 Wingo airlines · P5 7290 Depart at 10:09pm from Bogotá (BOG) Fly for 1h 2m Arrive at 11:11pm in Medellín (MDE)

Book Flight
US$178

4:23pm - 6:32am
Thu Apr 17th 2025

13h 9m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Thu Apr 17th 2025 Copa Airlines · CM 361 Depart at 4:23pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50pm in Panama (PTY)

Layover in Panama for 1h 26m

Thu Apr 17th 2025 Copa Airlines · CM 876 Depart at 9:16pm from Panama (PTY) Fly for 1h 39m Arrive at 10:55pm in Bogotá (BOG)

Layover in Bogotá for 6h 35m

Fri Apr 18th 2025 Wingo airlines · P5 7268 Depart at 5:30am from Bogotá (BOG) Fly for 1h 2m Arrive at 6:32am in Medellín (MDE)

Book Flight
US$182

10:23am - 8:55pm
Thu Apr 17th 2025

9h 32m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Thu Apr 17th 2025 Copa Airlines · CM 111 Depart at 10:23am from Guatemala City (GUA) Fly for 2h 26m Arrive at 1:49pm in Panama (PTY)

Layover in Panama for 1h 39m

Thu Apr 17th 2025 Copa Airlines · CM 413 Depart at 3:28pm from Panama (PTY) Fly for 1h 39m Arrive at 5:07pm in Bogotá (BOG)

Layover in Bogotá for 2h 46m

Thu Apr 17th 2025 Wingo airlines · P5 7276 Depart at 7:53pm from Bogotá (BOG) Fly for 1h 2m Arrive at 8:55pm in Medellín (MDE)

Book Flight
US$182

4:23am - 2:39pm
Fri Apr 18th 2025

9h 16m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Fri Apr 18th 2025 Copa Airlines · CM 407 Depart at 4:23am from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50am in Panama (PTY)

Layover in Panama for 1h 37m

Fri Apr 18th 2025 Copa Airlines · CM 332 Depart at 9:27am from Panama (PTY) Fly for 1h 39m Arrive at 11:06am in Bogotá (BOG)

Layover in Bogotá for 2h 28m

Fri Apr 18th 2025 JetSMART · JA 5135 Depart at 1:34pm from Bogotá (BOG) Fly for 1h 5m Arrive at 2:39pm in Medellín (MDE)

Book Flight
US$182

4:23am - 3:17pm
Fri Apr 18th 2025

9h 54m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Fri Apr 18th 2025 Copa Airlines · CM 407 Depart at 4:23am from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50am in Panama (PTY)

Layover in Panama for 1h 37m

Fri Apr 18th 2025 Copa Airlines · CM 332 Depart at 9:27am from Panama (PTY) Fly for 1h 39m Arrive at 11:06am in Bogotá (BOG)

Layover in Bogotá for 3h 6m

Fri Apr 18th 2025 JetSMART · JA 5112 Depart at 2:12pm from Bogotá (BOG) Fly for 1h 5m Arrive at 3:17pm in Medellín (MDE)

Book Flight
US$185

4:23pm - 6:32am
Wed Apr 16th 2025

13h 9m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Wed Apr 16th 2025 Copa Airlines · CM 361 Depart at 4:23pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50pm in Panama (PTY)

Layover in Panama for 2h 37m

Wed Apr 16th 2025 Copa Airlines · CM 430 Depart at 10:27pm from Panama (PTY) Fly for 1h 39m Arrive at 12:06am in Bogotá (BOG)

Layover in Bogotá for 5h 24m

Thu Apr 17th 2025 Wingo airlines · P5 7268 Depart at 5:30am from Bogotá (BOG) Fly for 1h 2m Arrive at 6:32am in Medellín (MDE)

Book Flight
US$188

7:09am - 4:35pm
Thu Apr 17th 2025

8h 26m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Thu Apr 17th 2025 Copa Airlines · CM 389 Depart at 7:09am from Guatemala City (GUA) Fly for 2h 27m Arrive at 10:36am in Panama (PTY)

Layover in Panama for 1h 14m

Thu Apr 17th 2025 Copa Airlines · CM 415 Depart at 11:50am from Panama (PTY) Fly for 1h 39m Arrive at 1:29pm in Bogotá (BOG)

Layover in Bogotá for 2h 1m

Thu Apr 17th 2025 JetSMART · JA 5118 Depart at 3:30pm from Bogotá (BOG) Fly for 1h 5m Arrive at 4:35pm in Medellín (MDE)

Book Flight
US$190

10:23am - 5:01pm
Fri Apr 18th 2025

5h 38m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Fri Apr 18th 2025 Copa Airlines · CM 111 Depart at 10:23am from Guatemala City (GUA) Fly for 2h 26m Arrive at 1:49pm in Panama (PTY)

Layover in Panama for 1h 47m

Fri Apr 18th 2025 Copa Airlines · CM 156 Depart at 3:36pm from Panama (PTY) Fly for 1h 25m Arrive at 5:01pm in Medellín (MDE)

Book Flight
US$190

7:09am - 2:15pm
Fri Apr 18th 2025

6h 6m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Fri Apr 18th 2025 Copa Airlines · CM 389 Depart at 7:09am from Guatemala City (GUA) Fly for 2h 27m Arrive at 10:36am in Panama (PTY)

Layover in Panama for 2h 14m

Fri Apr 18th 2025 Copa Airlines · CM 502 Depart at 12:50pm from Panama (PTY) Fly for 1h 25m Arrive at 2:15pm in Medellín (MDE)

Book Flight
US$191

7:09am - 4:45pm
Thu Apr 17th 2025

8h 36m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Thu Apr 17th 2025 Copa Airlines · CM 389 Depart at 7:09am from Guatemala City (GUA) Fly for 2h 27m Arrive at 10:36am in Panama (PTY)

Layover in Panama for 1h 14m

Thu Apr 17th 2025 Copa Airlines · CM 415 Depart at 11:50am from Panama (PTY) Fly for 1h 39m Arrive at 1:29pm in Bogotá (BOG)

Layover in Bogotá for 2h 16m

Thu Apr 17th 2025 Avianca · AV 9324 Depart at 3:45pm from Bogotá (BOG) Fly for 1h 0m Arrive at 4:45pm in Medellín (MDE)

Book Flight
US$192

4:23am - 10:29am
Wed Apr 16th 2025

5h 6m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Copa Airlines · CM 407 Depart at 4:23am from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50am in Panama (PTY)

Layover in Panama for 1h 14m

Wed Apr 16th 2025 Copa Airlines · CM 855 Depart at 9:04am from Panama (PTY) Fly for 1h 25m Arrive at 10:29am in Medellín (MDE)

Book Flight
US$192

4:23am - 10:56am
Wed Apr 16th 2025

5h 33m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Copa Airlines · CM 407 Depart at 4:23am from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50am in Panama (PTY)

Layover in Panama for 1h 41m

Wed Apr 16th 2025 Copa Airlines · CM 397 Depart at 9:31am from Panama (PTY) Fly for 1h 25m Arrive at 10:56am in Medellín (MDE)

Book Flight
US$193

7:09am - 5:57pm
Fri Apr 18th 2025

9h 48m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Fri Apr 18th 2025 Copa Airlines · CM 389 Depart at 7:09am from Guatemala City (GUA) Fly for 2h 27m Arrive at 10:36am in Panama (PTY)

Layover in Panama for 1h 14m

Fri Apr 18th 2025 Copa Airlines · CM 415 Depart at 11:50am from Panama (PTY) Fly for 1h 39m Arrive at 1:29pm in Bogotá (BOG)

Layover in Bogotá for 3h 26m

Fri Apr 18th 2025 Wingo airlines · P5 7274 Depart at 4:55pm from Bogotá (BOG) Fly for 1h 2m Arrive at 5:57pm in Medellín (MDE)

Book Flight
US$197

7:09am - 4:45pm
Fri Apr 18th 2025

8h 36m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Fri Apr 18th 2025 Copa Airlines · CM 389 Depart at 7:09am from Guatemala City (GUA) Fly for 2h 27m Arrive at 10:36am in Panama (PTY)

Layover in Panama for 1h 14m

Fri Apr 18th 2025 Copa Airlines · CM 415 Depart at 11:50am from Panama (PTY) Fly for 1h 39m Arrive at 1:29pm in Bogotá (BOG)

Layover in Bogotá for 2h 16m

Fri Apr 18th 2025 Avianca · AV 9324 Depart at 3:45pm from Bogotá (BOG) Fly for 1h 0m Arrive at 4:45pm in Medellín (MDE)

Book Flight
US$197

10:23am - 10:08pm
Fri Apr 18th 2025

10h 45m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Fri Apr 18th 2025 Copa Airlines · CM 111 Depart at 10:23am from Guatemala City (GUA) Fly for 2h 26m Arrive at 1:49pm in Panama (PTY)

Layover in Panama for 1h 39m

Fri Apr 18th 2025 Copa Airlines · CM 413 Depart at 3:28pm from Panama (PTY) Fly for 1h 39m Arrive at 5:07pm in Bogotá (BOG)

Layover in Bogotá for 3h 59m

Fri Apr 18th 2025 Avianca · AV 9250 Depart at 9:06pm from Bogotá (BOG) Fly for 1h 2m Arrive at 10:08pm in Medellín (MDE)

Book Flight
US$199

7:09am - 5:05pm
Wed Apr 16th 2025

8h 56m
Guatemala City (GUA) → Medellín (EOH)

2 Stops

Wed Apr 16th 2025 Copa Airlines · CM 389 Depart at 7:09am from Guatemala City (GUA) Fly for 2h 27m Arrive at 10:36am in Panama (PTY)

Layover in Panama for 1h 14m

Wed Apr 16th 2025 Copa Airlines · CM 415 Depart at 11:50am from Panama (PTY) Fly for 1h 39m Arrive at 1:29pm in Bogotá (BOG)

Layover in Bogotá for 2h 27m

Wed Apr 16th 2025 SATENA · 9R 8616 Depart at 3:56pm from Bogotá (BOG) Fly for 1h 9m Arrive at 5:05pm in Medellín (EOH)

Book Flight
US$203

8:45am - 7:40pm
Mon Apr 21st 2025

9h 55m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Mon Apr 21st 2025 Arajet · DM 4601 Depart at 8:45am from Guatemala City (GUA) Fly for 3h 34m Arrive at 2:19pm in Santo Domingo (SDQ)

Layover in Santo Domingo for 3h 46m

Mon Apr 21st 2025 Arajet · DM 1736 Depart at 6:05pm from Santo Domingo (SDQ) Fly for 2h 35m Arrive at 7:40pm in Medellín (MDE)

Book Flight
US$205

8:20pm - 2:05am
Mon Apr 21st 2025

4h 45m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Mon Apr 21st 2025 Avianca · AV 589 Depart at 8:20pm from Guatemala City (GUA) Fly for 0h 45m Arrive at 9:05pm in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Mon Apr 21st 2025 Avianca · AV 369 Depart at 10:20pm from San Salvador (SAL) Fly for 2h 45m Arrive at 2:05am in Medellín (MDE)

Book Flight
US$205

4:35pm - 6:40am
Fri Apr 18th 2025

13h 5m
Guatemala City (GUA) → Medellín (EOH)

1 Stop

Fri Apr 18th 2025 Avianca · AV 35 Depart at 4:35pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:50pm in Bogotá (BOG)

Layover in Bogotá for 8h 40m

Sat Apr 19th 2025 Clic · VE 9104 Depart at 5:30am from Bogotá (BOG) Fly for 1h 10m Arrive at 6:40am in Medellín (EOH)

Book Flight
US$206

4:23pm - 6:14am
Wed Apr 16th 2025

12h 51m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Wed Apr 16th 2025 Copa Airlines · CM 361 Depart at 4:23pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50pm in Panama (PTY)

Layover in Panama for 2h 37m

Wed Apr 16th 2025 Copa Airlines · CM 430 Depart at 10:27pm from Panama (PTY) Fly for 1h 39m Arrive at 12:06am in Bogotá (BOG)

Layover in Bogotá for 5h 9m

Thu Apr 17th 2025 Avianca · AV 9252 Depart at 5:15am from Bogotá (BOG) Fly for 0h 59m Arrive at 6:14am in Medellín (MDE)

Book Flight
US$210

9:40am - 4:12pm
Fri Apr 18th 2025

5h 32m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Fri Apr 18th 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 1h 14m

Fri Apr 18th 2025 Avianca · AV 9326 Depart at 3:09pm from Bogotá (BOG) Fly for 1h 3m Arrive at 4:12pm in Medellín (MDE)

Book Flight
US$211

4:23pm - 6:40am
Wed Apr 16th 2025

13h 17m
Guatemala City (GUA) → Medellín (EOH)

2 Stops

Wed Apr 16th 2025 Copa Airlines · CM 361 Depart at 4:23pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50pm in Panama (PTY)

Layover in Panama for 2h 37m

Wed Apr 16th 2025 Copa Airlines · CM 430 Depart at 10:27pm from Panama (PTY) Fly for 1h 39m Arrive at 12:06am in Bogotá (BOG)

Layover in Bogotá for 5h 24m

Thu Apr 17th 2025 Clic · VE 9104 Depart at 5:30am from Bogotá (BOG) Fly for 1h 10m Arrive at 6:40am in Medellín (EOH)

Book Flight
US$224

9:40am - 9:29pm
Mon Apr 21st 2025

10h 49m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Mon Apr 21st 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 2h 6m

Mon Apr 21st 2025 Avianca · AV 9839 Depart at 4:01pm from Bogotá (BOG) Fly for 1h 3m Arrive at 5:04pm in Pereira (PEI)

Layover in Pereira for 3h 42m

Mon Apr 21st 2025 Avianca · AV 9618 Depart at 8:46pm from Pereira (PEI) Fly for 0h 43m Arrive at 9:29pm in Medellín (MDE)

Book Flight
US$225

9:40am - 6:01pm
Thu Apr 17th 2025

7h 21m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Thu Apr 17th 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 3h 5m

Thu Apr 17th 2025 Avianca · AV 9268 Depart at 5:00pm from Bogotá (BOG) Fly for 1h 1m Arrive at 6:01pm in Medellín (MDE)

Book Flight
US$225

6:35am - 3:26pm
Thu Apr 17th 2025

7h 51m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Thu Apr 17th 2025 Avianca · AV 165 Depart at 6:35am from Guatemala City (GUA) Fly for 3h 15m Arrive at 10:50am in Bogotá (BOG)

Layover in Bogotá for 3h 34m

Thu Apr 17th 2025 Wingo airlines · P5 7272 Depart at 2:24pm from Bogotá (BOG) Fly for 1h 2m Arrive at 3:26pm in Medellín (MDE)

Book Flight
US$231

9:40am - 5:16pm
Mon Apr 21st 2025

6h 36m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Mon Apr 21st 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 2h 19m

Mon Apr 21st 2025 Wingo airlines · P5 7274 Depart at 4:14pm from Bogotá (BOG) Fly for 1h 2m Arrive at 5:16pm in Medellín (MDE)

Book Flight
US$231

9:40am - 5:26pm
Thu Apr 17th 2025

6h 46m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Thu Apr 17th 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 2h 30m

Thu Apr 17th 2025 Avianca · AV 9304 Depart at 4:25pm from Bogotá (BOG) Fly for 1h 1m Arrive at 5:26pm in Medellín (MDE)

Book Flight
US$231

9:40am - 5:57pm
Fri Apr 18th 2025

7h 17m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Fri Apr 18th 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 3h 0m

Fri Apr 18th 2025 Wingo airlines · P5 7274 Depart at 4:55pm from Bogotá (BOG) Fly for 1h 2m Arrive at 5:57pm in Medellín (MDE)

Book Flight
US$231

6:35am - 3:00pm
Thu Apr 17th 2025

7h 25m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Thu Apr 17th 2025 Avianca · AV 165 Depart at 6:35am from Guatemala City (GUA) Fly for 3h 15m Arrive at 10:50am in Bogotá (BOG)

Layover in Bogotá for 3h 15m

Thu Apr 17th 2025 LATAM Airlines · LA 4020 Depart at 2:05pm from Bogotá (BOG) Fly for 0h 55m Arrive at 3:00pm in Medellín (MDE)

Book Flight
US$231

6:35am - 3:17pm
Thu Apr 17th 2025

7h 42m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Thu Apr 17th 2025 Avianca · AV 165 Depart at 6:35am from Guatemala City (GUA) Fly for 3h 15m Arrive at 10:50am in Bogotá (BOG)

Layover in Bogotá for 3h 30m

Thu Apr 17th 2025 Avianca · AV 9306 Depart at 2:20pm from Bogotá (BOG) Fly for 0h 57m Arrive at 3:17pm in Medellín (MDE)

Book Flight
US$231

6:35am - 11:29pm
Sat Apr 19th 2025

15h 54m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Avianca · AV 165 Depart at 6:35am from Guatemala City (GUA) Fly for 3h 15m Arrive at 10:50am in Bogotá (BOG)

Layover in Bogotá for 11h 37m

Sat Apr 19th 2025 Wingo airlines · P5 7290 Depart at 10:27pm from Bogotá (BOG) Fly for 1h 2m Arrive at 11:29pm in Medellín (MDE)

Book Flight
US$235

6:35am - 4:12pm
Sat Apr 19th 2025

8h 37m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Avianca · AV 165 Depart at 6:35am from Guatemala City (GUA) Fly for 3h 15m Arrive at 10:50am in Bogotá (BOG)

Layover in Bogotá for 4h 19m

Sat Apr 19th 2025 Avianca · AV 9326 Depart at 3:09pm from Bogotá (BOG) Fly for 1h 3m Arrive at 4:12pm in Medellín (MDE)

Book Flight
US$235

6:35am - 5:26pm
Sat Apr 19th 2025

9h 51m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Avianca · AV 165 Depart at 6:35am from Guatemala City (GUA) Fly for 3h 15m Arrive at 10:50am in Bogotá (BOG)

Layover in Bogotá for 5h 35m

Sat Apr 19th 2025 Avianca · AV 9304 Depart at 4:25pm from Bogotá (BOG) Fly for 1h 1m Arrive at 5:26pm in Medellín (MDE)

Book Flight
US$236

6:35am - 5:14pm
Sat Apr 19th 2025

9h 39m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Avianca · AV 165 Depart at 6:35am from Guatemala City (GUA) Fly for 3h 15m Arrive at 10:50am in Bogotá (BOG)

Layover in Bogotá for 5h 19m

Sat Apr 19th 2025 JetSMART · JA 5120 Depart at 4:09pm from Bogotá (BOG) Fly for 1h 5m Arrive at 5:14pm in Medellín (MDE)

Book Flight
US$238

4:35pm - 6:32am
Wed Apr 16th 2025

12h 57m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Avianca · AV 35 Depart at 4:35pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:50pm in Bogotá (BOG)

Layover in Bogotá for 8h 40m

Thu Apr 17th 2025 Wingo airlines · P5 7268 Depart at 5:30am from Bogotá (BOG) Fly for 1h 2m Arrive at 6:32am in Medellín (MDE)

Book Flight
US$245

4:23pm - 10:52pm
Fri Apr 18th 2025

5h 29m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Fri Apr 18th 2025 Copa Airlines · CM 361 Depart at 4:23pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50pm in Panama (PTY)

Layover in Panama for 1h 37m

Fri Apr 18th 2025 Copa Airlines · CM 155 Depart at 9:27pm from Panama (PTY) Fly for 1h 25m Arrive at 10:52pm in Medellín (MDE)

Book Flight
US$245

4:23am - 10:56am
Mon Apr 21st 2025

5h 33m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Mon Apr 21st 2025 Copa Airlines · CM 407 Depart at 4:23am from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50am in Panama (PTY)

Layover in Panama for 1h 41m

Mon Apr 21st 2025 Copa Airlines · CM 397 Depart at 9:31am from Panama (PTY) Fly for 1h 25m Arrive at 10:56am in Medellín (MDE)

Book Flight
US$245

6:35am - 3:17pm
Sat Apr 19th 2025

7h 42m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Avianca · AV 165 Depart at 6:35am from Guatemala City (GUA) Fly for 3h 15m Arrive at 10:50am in Bogotá (BOG)

Layover in Bogotá for 3h 30m

Sat Apr 19th 2025 Avianca · AV 9306 Depart at 2:20pm from Bogotá (BOG) Fly for 0h 57m Arrive at 3:17pm in Medellín (MDE)

Book Flight
US$247

4:23am - 10:29am
Sat Apr 19th 2025

5h 6m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Copa Airlines · CM 407 Depart at 4:23am from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50am in Panama (PTY)

Layover in Panama for 1h 14m

Sat Apr 19th 2025 Copa Airlines · CM 855 Depart at 9:04am from Panama (PTY) Fly for 1h 25m Arrive at 10:29am in Medellín (MDE)

Book Flight
US$247

7:09am - 2:15pm
Sat Apr 19th 2025

6h 6m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Copa Airlines · CM 389 Depart at 7:09am from Guatemala City (GUA) Fly for 2h 27m Arrive at 10:36am in Panama (PTY)

Layover in Panama for 2h 14m

Sat Apr 19th 2025 Copa Airlines · CM 502 Depart at 12:50pm from Panama (PTY) Fly for 1h 25m Arrive at 2:15pm in Medellín (MDE)

Book Flight
US$247

4:23am - 5:00pm
Fri Apr 18th 2025

11h 37m
Guatemala City (GUA) → Medellín (EOH)

2 Stops

Fri Apr 18th 2025 Copa Airlines · CM 407 Depart at 4:23am from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50am in Panama (PTY)

Layover in Panama for 1h 37m

Fri Apr 18th 2025 Copa Airlines · CM 332 Depart at 9:27am from Panama (PTY) Fly for 1h 39m Arrive at 11:06am in Bogotá (BOG)

Layover in Bogotá for 4h 44m

Fri Apr 18th 2025 Clic · VE 9112 Depart at 3:50pm from Bogotá (BOG) Fly for 1h 10m Arrive at 5:00pm in Medellín (EOH)

Book Flight
US$247

1:12pm - 8:18am
Sat Apr 19th 2025

18h 6m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Copa Airlines · CM 384 Depart at 1:12pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 4:39pm in Panama (PTY)

Layover in Panama for 14h 14m

Sun Apr 20th 2025 Copa Airlines · CM 150 Depart at 6:53am from Panama (PTY) Fly for 1h 25m Arrive at 8:18am in Medellín (MDE)

Book Flight
US$250

9:40am - 11:29pm
Sat Apr 19th 2025

12h 49m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 8h 32m

Sat Apr 19th 2025 Wingo airlines · P5 7290 Depart at 10:27pm from Bogotá (BOG) Fly for 1h 2m Arrive at 11:29pm in Medellín (MDE)

Book Flight
US$253

6:35am - 1:54pm
Sat Apr 19th 2025

6h 19m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Avianca · AV 165 Depart at 6:35am from Guatemala City (GUA) Fly for 3h 15m Arrive at 10:50am in Bogotá (BOG)

Layover in Bogotá for 2h 10m

Sat Apr 19th 2025 Avianca · AV 9328 Depart at 1:00pm from Bogotá (BOG) Fly for 0h 54m Arrive at 1:54pm in Medellín (MDE)

Book Flight
US$254

9:40am - 5:26pm
Sat Apr 19th 2025

6h 46m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 2h 30m

Sat Apr 19th 2025 Avianca · AV 9304 Depart at 4:25pm from Bogotá (BOG) Fly for 1h 1m Arrive at 5:26pm in Medellín (MDE)

Book Flight
US$254

9:40am - 5:14pm
Sat Apr 19th 2025

6h 34m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 2h 14m

Sat Apr 19th 2025 JetSMART · JA 5120 Depart at 4:09pm from Bogotá (BOG) Fly for 1h 5m Arrive at 5:14pm in Medellín (MDE)

Book Flight
US$258

9:45pm - 2:00pm
Fri Apr 18th 2025

15h 15m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Fri Apr 18th 2025 Avianca · AV 651 Depart at 9:45pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 11:15pm in San José (SJO)

Layover in San José for 11h 45m

Sat Apr 19th 2025 Avianca · AV 25 Depart at 11:00am from San José (SJO) Fly for 2h 0m Arrive at 2:00pm in Medellín (MDE)

Book Flight
US$260

4:35pm - 6:14am
Wed Apr 16th 2025

12h 39m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Avianca · AV 35 Depart at 4:35pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:50pm in Bogotá (BOG)

Layover in Bogotá for 8h 25m

Thu Apr 17th 2025 Avianca · AV 9252 Depart at 5:15am from Bogotá (BOG) Fly for 0h 59m Arrive at 6:14am in Medellín (MDE)

Book Flight
US$262

7:09am - 5:00pm
Fri Apr 18th 2025

8h 51m
Guatemala City (GUA) → Medellín (EOH)

2 Stops

Fri Apr 18th 2025 Copa Airlines · CM 389 Depart at 7:09am from Guatemala City (GUA) Fly for 2h 27m Arrive at 10:36am in Panama (PTY)

Layover in Panama for 1h 14m

Fri Apr 18th 2025 Copa Airlines · CM 415 Depart at 11:50am from Panama (PTY) Fly for 1h 39m Arrive at 1:29pm in Bogotá (BOG)

Layover in Bogotá for 2h 21m

Fri Apr 18th 2025 Clic · VE 9112 Depart at 3:50pm from Bogotá (BOG) Fly for 1h 10m Arrive at 5:00pm in Medellín (EOH)

Book Flight
US$265

6:35am - 2:05pm
Sat Apr 19th 2025

6h 30m
Guatemala City (GUA) → Medellín (EOH)

1 Stop

Sat Apr 19th 2025 Avianca · AV 165 Depart at 6:35am from Guatemala City (GUA) Fly for 3h 15m Arrive at 10:50am in Bogotá (BOG)

Layover in Bogotá for 2h 5m

Sat Apr 19th 2025 Clic · VE 9110 Depart at 12:55pm from Bogotá (BOG) Fly for 1h 10m Arrive at 2:05pm in Medellín (EOH)

Book Flight
US$265

4:35pm - 6:40am
Wed Apr 16th 2025

13h 5m
Guatemala City (GUA) → Medellín (EOH)

1 Stop

Wed Apr 16th 2025 Avianca · AV 35 Depart at 4:35pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:50pm in Bogotá (BOG)

Layover in Bogotá for 8h 40m

Thu Apr 17th 2025 Clic · VE 9104 Depart at 5:30am from Bogotá (BOG) Fly for 1h 10m Arrive at 6:40am in Medellín (EOH)

Book Flight
US$266

6:35am - 1:03pm
Thu Apr 17th 2025

5h 28m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Thu Apr 17th 2025 Avianca · AV 165 Depart at 6:35am from Guatemala City (GUA) Fly for 3h 15m Arrive at 10:50am in Bogotá (BOG)

Layover in Bogotá for 1h 16m

Thu Apr 17th 2025 Avianca · AV 9330 Depart at 12:06pm from Bogotá (BOG) Fly for 0h 57m Arrive at 1:03pm in Medellín (MDE)

Book Flight
US$266

9:40am - 4:12pm
Mon Apr 21st 2025

5h 32m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Mon Apr 21st 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 1h 14m

Mon Apr 21st 2025 Avianca · AV 9326 Depart at 3:09pm from Bogotá (BOG) Fly for 1h 3m Arrive at 4:12pm in Medellín (MDE)

Book Flight
US$266

9:40am - 4:12pm
Thu Apr 17th 2025

5h 32m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Thu Apr 17th 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 1h 14m

Thu Apr 17th 2025 Avianca · AV 9326 Depart at 3:09pm from Bogotá (BOG) Fly for 1h 3m Arrive at 4:12pm in Medellín (MDE)

Book Flight
US$266

4:35pm - 11:42pm
Wed Apr 16th 2025

6h 7m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Avianca · AV 35 Depart at 4:35pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:50pm in Bogotá (BOG)

Layover in Bogotá for 1h 50m

Wed Apr 16th 2025 Avianca · AV 9342 Depart at 10:40pm from Bogotá (BOG) Fly for 1h 2m Arrive at 11:42pm in Medellín (MDE)

Book Flight
US$268

9:40am - 5:10pm
Mon Apr 21st 2025

6h 30m
Guatemala City (GUA) → Medellín (EOH)

1 Stop

Mon Apr 21st 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 2h 5m

Mon Apr 21st 2025 Clic · VE 9112 Depart at 4:00pm from Bogotá (BOG) Fly for 1h 10m Arrive at 5:10pm in Medellín (EOH)

Book Flight
US$270

9:45pm - 9:53am
Thu Apr 17th 2025

11h 8m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Thu Apr 17th 2025 Avianca · AV 641 Depart at 9:45pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 11:15pm in San José (SJO)

Layover in San José for 7h 38m

Fri Apr 18th 2025 Avianca · AV 157 Depart at 6:53am from San José (SJO) Fly for 2h 0m Arrive at 9:53am in Medellín (MDE)

Book Flight
US$275

7:09am - 2:15pm
Mon Apr 21st 2025

6h 6m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Mon Apr 21st 2025 Copa Airlines · CM 389 Depart at 7:09am from Guatemala City (GUA) Fly for 2h 27m Arrive at 10:36am in Panama (PTY)

Layover in Panama for 2h 14m

Mon Apr 21st 2025 Copa Airlines · CM 502 Depart at 12:50pm from Panama (PTY) Fly for 1h 25m Arrive at 2:15pm in Medellín (MDE)

Book Flight
US$277

4:23am - 2:15pm
Wed Apr 16th 2025

8h 52m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Copa Airlines · CM 407 Depart at 4:23am from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50am in Panama (PTY)

Layover in Panama for 5h 0m

Wed Apr 16th 2025 Copa Airlines · CM 502 Depart at 12:50pm from Panama (PTY) Fly for 1h 25m Arrive at 2:15pm in Medellín (MDE)

Book Flight
US$281

6:35am - 1:59pm
Sat Apr 19th 2025

6h 24m
Guatemala City (GUA) → Medellín (EOH)

1 Stop

Sat Apr 19th 2025 Avianca · AV 165 Depart at 6:35am from Guatemala City (GUA) Fly for 3h 15m Arrive at 10:50am in Bogotá (BOG)

Layover in Bogotá for 2h 0m

Sat Apr 19th 2025 SATENA · 9R 8767 Depart at 12:50pm from Bogotá (BOG) Fly for 1h 9m Arrive at 1:59pm in Medellín (EOH)

Book Flight
US$282

4:23am - 2:35pm
Wed Apr 16th 2025

9h 12m
Guatemala City (GUA) → Medellín (EOH)

2 Stops

Wed Apr 16th 2025 Copa Airlines · CM 407 Depart at 4:23am from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50am in Panama (PTY)

Layover in Panama for 1h 37m

Wed Apr 16th 2025 Copa Airlines · CM 332 Depart at 9:27am from Panama (PTY) Fly for 1h 39m Arrive at 11:06am in Bogotá (BOG)

Layover in Bogotá for 2h 34m

Wed Apr 16th 2025 SATENA · 9R 8767 Depart at 1:40pm from Bogotá (BOG) Fly for 0h 55m Arrive at 2:35pm in Medellín (EOH)

Book Flight
US$283

9:40am - 5:15pm
Sat Apr 19th 2025

6h 35m
Guatemala City (GUA) → Medellín (EOH)

1 Stop

Sat Apr 19th 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 2h 10m

Sat Apr 19th 2025 Clic · VE 9112 Depart at 4:05pm from Bogotá (BOG) Fly for 1h 10m Arrive at 5:15pm in Medellín (EOH)

Book Flight
US$293

9:40am - 4:55pm
Sat Apr 19th 2025

6h 15m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 2h 5m

Sat Apr 19th 2025 LATAM Airlines · LA 4016 Depart at 4:00pm from Bogotá (BOG) Fly for 0h 55m Arrive at 4:55pm in Medellín (MDE)

Book Flight
US$295

4:35pm - 6:30am
Mon Apr 21st 2025

12h 55m
Guatemala City (GUA) → Medellín (EOH)

1 Stop

Mon Apr 21st 2025 Avianca · AV 35 Depart at 4:35pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:50pm in Bogotá (BOG)

Layover in Bogotá for 8h 30m

Tue Apr 22nd 2025 Clic · VE 9104 Depart at 5:20am from Bogotá (BOG) Fly for 1h 10m Arrive at 6:30am in Medellín (EOH)

Book Flight
US$298

10:00am - 4:55pm
Thu Apr 17th 2025

5h 55m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Thu Apr 17th 2025 Avianca · AV 573 Depart at 10:00am from Guatemala City (GUA) Fly for 0h 50m Arrive at 10:50am in San Salvador (SAL)

Layover in San Salvador for 1h 0m

Thu Apr 17th 2025 Avianca · AV 317 Depart at 11:50am from San Salvador (SAL) Fly for 1h 55m Arrive at 2:45pm in Panama (PTY)

Layover in Panama for 0h 55m

Thu Apr 17th 2025 Avianca · AV 317 Depart at 3:40pm from Panama (PTY) Fly for 1h 15m Arrive at 4:55pm in Medellín (MDE)

Book Flight
US$298

5:20am - 12:30pm
Fri Apr 18th 2025

6h 10m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Fri Apr 18th 2025 Avianca · AV 579 Depart at 5:20am from Guatemala City (GUA) Fly for 0h 50m Arrive at 6:10am in San Salvador (SAL)

Layover in San Salvador for 1h 20m

Fri Apr 18th 2025 Avianca · AV 323 Depart at 7:30am from San Salvador (SAL) Fly for 1h 55m Arrive at 10:25am in Panama (PTY)

Layover in Panama for 0h 55m

Fri Apr 18th 2025 Avianca · AV 323 Depart at 11:20am from Panama (PTY) Fly for 1h 10m Arrive at 12:30pm in Medellín (MDE)

Book Flight
US$300

7:50am - 2:00pm
Sat Apr 19th 2025

5h 10m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Avianca · AV 653 Depart at 7:50am from Guatemala City (GUA) Fly for 1h 30m Arrive at 9:20am in San José (SJO)

Layover in San José for 1h 40m

Sat Apr 19th 2025 Avianca · AV 25 Depart at 11:00am from San José (SJO) Fly for 2h 0m Arrive at 2:00pm in Medellín (MDE)

Book Flight
US$300

7:50am - 2:00pm
Mon Apr 21st 2025

5h 10m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Mon Apr 21st 2025 Avianca · AV 653 Depart at 7:50am from Guatemala City (GUA) Fly for 1h 30m Arrive at 9:20am in San José (SJO)

Layover in San José for 1h 40m

Mon Apr 21st 2025 Avianca · AV 25 Depart at 11:00am from San José (SJO) Fly for 2h 0m Arrive at 2:00pm in Medellín (MDE)

Book Flight
US$301

6:35am - 1:03pm
Sat Apr 19th 2025

5h 28m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Avianca · AV 165 Depart at 6:35am from Guatemala City (GUA) Fly for 3h 15m Arrive at 10:50am in Bogotá (BOG)

Layover in Bogotá for 1h 16m

Sat Apr 19th 2025 Avianca · AV 9330 Depart at 12:06pm from Bogotá (BOG) Fly for 0h 57m Arrive at 1:03pm in Medellín (MDE)

Book Flight
US$301

9:40am - 4:12pm
Sat Apr 19th 2025

5h 32m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 1h 14m

Sat Apr 19th 2025 Avianca · AV 9326 Depart at 3:09pm from Bogotá (BOG) Fly for 1h 3m Arrive at 4:12pm in Medellín (MDE)

Book Flight
US$301

4:35pm - 11:17pm
Wed Apr 16th 2025

5h 42m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Avianca · AV 35 Depart at 4:35pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:50pm in Bogotá (BOG)

Layover in Bogotá for 1h 30m

Wed Apr 16th 2025 Avianca · AV 8449 Depart at 10:20pm from Bogotá (BOG) Fly for 0h 57m Arrive at 11:17pm in Medellín (MDE)

Book Flight
US$301

4:35pm - 11:17pm
Mon Apr 21st 2025

5h 42m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Mon Apr 21st 2025 Avianca · AV 35 Depart at 4:35pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:50pm in Bogotá (BOG)

Layover in Bogotá for 1h 30m

Mon Apr 21st 2025 Avianca · AV 8449 Depart at 10:20pm from Bogotá (BOG) Fly for 0h 57m Arrive at 11:17pm in Medellín (MDE)

Book Flight
US$331

8:20pm - 2:05am
Fri Apr 18th 2025

4h 45m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Fri Apr 18th 2025 Avianca · AV 557 Depart at 8:20pm from Guatemala City (GUA) Fly for 0h 45m Arrive at 9:05pm in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Fri Apr 18th 2025 Avianca · AV 369 Depart at 10:20pm from San Salvador (SAL) Fly for 2h 45m Arrive at 2:05am in Medellín (MDE)

Book Flight
US$335

7:50am - 2:00pm
Thu Apr 17th 2025

5h 10m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Thu Apr 17th 2025 Avianca · AV 653 Depart at 7:50am from Guatemala City (GUA) Fly for 1h 30m Arrive at 9:20am in San José (SJO)

Layover in San José for 1h 40m

Thu Apr 17th 2025 Avianca · AV 25 Depart at 11:00am from San José (SJO) Fly for 2h 0m Arrive at 2:00pm in Medellín (MDE)

Book Flight
US$335

6:10am - 2:00pm
Wed Apr 16th 2025

6h 50m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Avianca · AV 655 Depart at 6:10am from Guatemala City (GUA) Fly for 1h 30m Arrive at 7:40am in San José (SJO)

Layover in San José for 3h 20m

Wed Apr 16th 2025 Avianca · AV 25 Depart at 11:00am from San José (SJO) Fly for 2h 0m Arrive at 2:00pm in Medellín (MDE)

Book Flight
US$344

1:12pm - 7:58pm
Wed Apr 16th 2025

5h 46m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Copa Airlines · CM 384 Depart at 1:12pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 4:39pm in Panama (PTY)

Layover in Panama for 1h 54m

Wed Apr 16th 2025 Copa Airlines · CM 208 Depart at 6:33pm from Panama (PTY) Fly for 1h 25m Arrive at 7:58pm in Medellín (MDE)

Book Flight
US$345

1:12pm - 7:58pm
Thu Apr 17th 2025

5h 46m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Thu Apr 17th 2025 Copa Airlines · CM 384 Depart at 1:12pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 4:39pm in Panama (PTY)

Layover in Panama for 1h 54m

Thu Apr 17th 2025 Copa Airlines · CM 208 Depart at 6:33pm from Panama (PTY) Fly for 1h 25m Arrive at 7:58pm in Medellín (MDE)

Book Flight
US$362

4:35pm - 6:49pm
Wed Apr 16th 2025

25h 14m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Avianca · AV 35 Depart at 4:35pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:50pm in Bogotá (BOG)

Layover in Bogotá for 21h 2m

Thu Apr 17th 2025 Avianca · AV 8534 Depart at 5:52pm from Bogotá (BOG) Fly for 0h 57m Arrive at 6:49pm in Medellín (MDE)

Book Flight
US$372

8:20pm - 2:05am
Thu Apr 17th 2025

4h 45m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Thu Apr 17th 2025 Avianca · AV 589 Depart at 8:20pm from Guatemala City (GUA) Fly for 0h 45m Arrive at 9:05pm in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Thu Apr 17th 2025 Avianca · AV 369 Depart at 10:20pm from San Salvador (SAL) Fly for 2h 45m Arrive at 2:05am in Medellín (MDE)

Book Flight
US$524

8:20pm - 2:05am
Sat Apr 19th 2025

4h 45m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sat Apr 19th 2025 Avianca · AV 589 Depart at 8:20pm from Guatemala City (GUA) Fly for 0h 45m Arrive at 9:05pm in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Sat Apr 19th 2025 Avianca · AV 369 Depart at 10:20pm from San Salvador (SAL) Fly for 2h 45m Arrive at 2:05am in Medellín (MDE)

Book Flight
US$524

8:20pm - 2:05am
Wed Apr 16th 2025

4h 45m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Wed Apr 16th 2025 Avianca · AV 589 Depart at 8:20pm from Guatemala City (GUA) Fly for 0h 45m Arrive at 9:05pm in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Wed Apr 16th 2025 Avianca · AV 369 Depart at 10:20pm from San Salvador (SAL) Fly for 2h 45m Arrive at 2:05am in Medellín (MDE)

Book Flight
US$586

8:20pm - 2:05am
Sun Apr 20th 2025

4h 45m
Guatemala City (GUA) → Medellín (MDE)

1 Stop

Sun Apr 20th 2025 Avianca · AV 589 Depart at 8:20pm from Guatemala City (GUA) Fly for 0h 45m Arrive at 9:05pm in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Sun Apr 20th 2025 Avianca · AV 369 Depart at 10:20pm from San Salvador (SAL) Fly for 2h 45m Arrive at 2:05am in Medellín (MDE)

Book Flight
US$652

9:40am - 7:25pm
Wed Apr 16th 2025

8h 45m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Wed Apr 16th 2025 Avianca · AV 743 Depart at 9:40am from Guatemala City (GUA) Fly for 3h 15m Arrive at 1:55pm in Bogotá (BOG)

Layover in Bogotá for 1h 14m

Wed Apr 16th 2025 Avianca · AV 9205 Depart at 3:09pm from Bogotá (BOG) Fly for 1h 7m Arrive at 4:16pm in Cali (CLO)

Layover in Cali for 2h 14m

Wed Apr 16th 2025 Avianca · AV 9474 Depart at 6:30pm from Cali (CLO) Fly for 0h 55m Arrive at 7:25pm in Medellín (MDE)

Book Flight
US$735

5:20am - 10:26pm
Wed Apr 16th 2025

40h 6m
Guatemala City (GUA) → Medellín (MDE)

2 Stops

Wed Apr 16th 2025 Avianca · AV 579 Depart at 5:20am from Guatemala City (GUA) Fly for 0h 50m Arrive at 6:10am in San Salvador (SAL)

Layover in San Salvador for 15h 55m

Wed Apr 16th 2025 Avianca · AV 113 Depart at 10:05pm from San Salvador (SAL) Fly for 2h 50m Arrive at 1:55am in Bogotá (BOG)

Layover in Bogotá for 19h 29m

Thu Apr 17th 2025 Avianca · AV 9314 Depart at 9:24pm from Bogotá (BOG) Fly for 1h 2m Arrive at 10:26pm in Medellín (MDE)

Book Flight

Sarah Belizaire

@sarahbb1

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John Ford

@eyupitsjohn

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Roaming Sonaa

@roamingsonaa

For people wanting to maximize their trips, Flightlist is my newest travel hack for uncovering the coolest routes at irresistible prices. No stress, no annoying ads — just seamless flight booking with amazing functionality. It's designed for remote workers, backpackers, and people living abroad.

Read Sonaa's 7 Amazing Skyscanner Alternatives for Booking Travel

ANDY TRAVELS

@andy_travels

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Travel With Bender

@travelwitbender

Did you spot my recent article about how to score cheap one way flights? ✈️ FlightList is my new secret tool for discovering cheap routes, within a departure date range. Plus you can also search by country/region for departures & destinations. Powerful! 💪

Read Josh's Ultimate Guide To Find Cheap One Way Flights

Wesley Mergard

@travel.with.wes

One useful tool I've found for evaluating different departure and return dates is called FlightList.io. You can quickly scan different travel date ranges, carriers and one way flight options to easily determine the cheapest flight combinations for your trip.

Read Wesley's My Best Cheap Flight Hacks (Why Pay More?)

Cheap Flights from Guatemala to Rio Negro (GT to MDE)

Sarah Belizaire

John Ford

Roaming Sonaa

ANDY TRAVELS

Travel With Bender

Wesley Mergard

Latest Cheap Flight Searches

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Why I Built FlightList & Solved My Own Problem

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