Cheap Flights from Spain to Panama (ES to PA)

Discover more affordable routes and cheaper dates from Spain to Panama (ES to PA) within a date range.

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€336.19

9:45am - 6:40pm
Sun Mar 30th 2025

38h 55m
Las Palmas (LPA) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Ryanair · FR 5499 Depart at 9:45am from Las Palmas (LPA) Fly for 2h 35m Arrive at 12:20pm in Porto (OPO)

Layover in Porto for 23h 15m

Mon Mar 31st 2025 Air Europa · UX 1146 Depart at 11:35am from Porto (OPO) Fly for 1h 10m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€336.94

6:05am - 6:40pm
Mon Mar 31st 2025

19h 35m
Palma, Majorca (PMI) → Panama (PTY)

2 Stops

Mon Mar 31st 2025 Ryanair · FR 6751 Depart at 6:05am from Palma, Majorca (PMI) Fly for 2h 0m Arrive at 7:05am in Porto (OPO)

Layover in Porto for 4h 30m

Mon Mar 31st 2025 Air Europa · UX 1146 Depart at 11:35am from Porto (OPO) Fly for 1h 10m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€339.19

7:50am - 6:40pm
Sun Mar 30th 2025

17h 50m
Barcelona (BCN) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Ryanair · FR 4587 Depart at 7:50am from Barcelona (BCN) Fly for 2h 0m Arrive at 8:50am in Porto (OPO)

Layover in Porto for 2h 45m

Sun Mar 30th 2025 Air Europa · UX 1146 Depart at 11:35am from Porto (OPO) Fly for 1h 10m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Sun Mar 30th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€339.83

7:50pm - 6:40pm
Mon Mar 31st 2025

29h 50m
Alicante (ALC) → Panama (PTY)

2 Stops

Mon Mar 31st 2025 Ryanair · FR 2029 Depart at 7:50pm from Alicante (ALC) Fly for 1h 40m Arrive at 8:30pm in Porto (OPO)

Layover in Porto for 15h 5m

Tue Apr 1st 2025 Air Europa · UX 1146 Depart at 11:35am from Porto (OPO) Fly for 1h 10m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Tue Apr 1st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€341.25

9:45am - 6:40pm
Sun Mar 30th 2025

15h 55m
Seville (SVQ) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Ryanair · FR 5509 Depart at 9:45am from Seville (SVQ) Fly for 1h 20m Arrive at 10:05am in Porto (OPO)

Layover in Porto for 1h 30m

Sun Mar 30th 2025 Air Europa · UX 1146 Depart at 11:35am from Porto (OPO) Fly for 1h 10m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Sun Mar 30th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€341.30

6:00am - 6:40pm
Sun Mar 30th 2025

19h 40m
Valencia (VLC) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Ryanair · FR 1769 Depart at 6:00am from Valencia (VLC) Fly for 1h 45m Arrive at 6:45am in Lisbon (LIS)

Layover in Lisbon for 4h 50m

Sun Mar 30th 2025 Air Europa · UX 1150 Depart at 11:35am from Lisbon (LIS) Fly for 1h 15m Arrive at 1:50pm in Madrid (MAD)

Layover in Madrid for 1h 15m

Sun Mar 30th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€342.19

8:45pm - 6:40pm
Sun Mar 30th 2025

28h 55m
Alicante (ALC) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Ryanair · FR 2942 Depart at 8:45pm from Alicante (ALC) Fly for 1h 40m Arrive at 9:25pm in Porto (OPO)

Layover in Porto for 14h 10m

Mon Mar 31st 2025 Air Europa · UX 1146 Depart at 11:35am from Porto (OPO) Fly for 1h 10m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€343.29

10:00pm - 6:40pm
Sun Mar 30th 2025

27h 40m
Málaga (AGP) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Ryanair · FR 3683 Depart at 10:00pm from Málaga (AGP) Fly for 1h 25m Arrive at 10:25pm in Lisbon (LIS)

Layover in Lisbon for 9h 15m

Mon Mar 31st 2025 Air Europa · UX 1152 Depart at 7:40am from Lisbon (LIS) Fly for 1h 15m Arrive at 9:55am in Madrid (MAD)

Layover in Madrid for 5h 10m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€345

7:00am - 6:40pm
Sun Mar 30th 2025

18h 40m
Barcelona (BCN) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Vueling · VY 8476 Depart at 7:00am from Barcelona (BCN) Fly for 2h 0m Arrive at 8:00am in Porto (OPO)

Layover in Porto for 3h 35m

Sun Mar 30th 2025 Air Europa · UX 1146 Depart at 11:35am from Porto (OPO) Fly for 1h 10m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Sun Mar 30th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€348.51

9:05am - 6:40pm
Mon Mar 31st 2025

16h 35m
Barcelona (BCN) → Panama (PTY)

2 Stops

Mon Mar 31st 2025 Ryanair · FR 4585 Depart at 9:05am from Barcelona (BCN) Fly for 2h 0m Arrive at 10:05am in Porto (OPO)

Layover in Porto for 1h 30m

Mon Mar 31st 2025 Air Europa · UX 1146 Depart at 11:35am from Porto (OPO) Fly for 1h 10m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€350

7:50pm - 6:40pm
Sun Mar 30th 2025

29h 50m
Bilbao (BIO) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Volotea · V7 3574 Depart at 7:50pm from Bilbao (BIO) Fly for 1h 20m Arrive at 8:10pm in Porto (OPO)

Layover in Porto for 15h 25m

Mon Mar 31st 2025 Air Europa · UX 1146 Depart at 11:35am from Porto (OPO) Fly for 1h 10m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€350

4:00pm - 6:40pm
Mon Mar 31st 2025

33h 40m
Barcelona (BCN) → Panama (PTY)

2 Stops

Mon Mar 31st 2025 Vueling · VY 8468 Depart at 4:00pm from Barcelona (BCN) Fly for 2h 5m Arrive at 5:05pm in Lisbon (LIS)

Layover in Lisbon for 18h 30m

Tue Apr 1st 2025 Air Europa · UX 1150 Depart at 11:35am from Lisbon (LIS) Fly for 1h 15m Arrive at 1:50pm in Madrid (MAD)

Layover in Madrid for 1h 15m

Tue Apr 1st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€354.41

8:05pm - 6:40pm
Mon Mar 31st 2025

29h 35m
Barcelona (BCN) → Panama (PTY)

2 Stops

Mon Mar 31st 2025 Ryanair · FR 4587 Depart at 8:05pm from Barcelona (BCN) Fly for 2h 0m Arrive at 9:05pm in Porto (OPO)

Layover in Porto for 14h 30m

Tue Apr 1st 2025 Air Europa · UX 1146 Depart at 11:35am from Porto (OPO) Fly for 1h 10m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Tue Apr 1st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€356

7:50pm - 6:40pm
Sun Mar 30th 2025

29h 50m
Palma, Majorca (PMI) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Vueling · VY 3436 Depart at 7:50pm from Palma, Majorca (PMI) Fly for 2h 10m Arrive at 9:00pm in Lisbon (LIS)

Layover in Lisbon for 10h 40m

Mon Mar 31st 2025 Air Europa · UX 1152 Depart at 7:40am from Lisbon (LIS) Fly for 1h 15m Arrive at 9:55am in Madrid (MAD)

Layover in Madrid for 5h 10m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€358

7:55pm - 6:40pm
Sun Mar 30th 2025

29h 45m
Asturias (OVD) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Volotea · V7 3594 Depart at 7:55pm from Asturias (OVD) Fly for 1h 25m Arrive at 8:20pm in Lisbon (LIS)

Layover in Lisbon for 11h 20m

Mon Mar 31st 2025 Air Europa · UX 1152 Depart at 7:40am from Lisbon (LIS) Fly for 1h 15m Arrive at 9:55am in Madrid (MAD)

Layover in Madrid for 5h 10m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€362

7:30pm - 6:40pm
Mon Mar 31st 2025

30h 10m
Barcelona (BCN) → Panama (PTY)

2 Stops

Mon Mar 31st 2025 Vueling · VY 8462 Depart at 7:30pm from Barcelona (BCN) Fly for 2h 10m Arrive at 8:40pm in Lisbon (LIS)

Layover in Lisbon for 14h 55m

Tue Apr 1st 2025 Air Europa · UX 1150 Depart at 11:35am from Lisbon (LIS) Fly for 1h 15m Arrive at 1:50pm in Madrid (MAD)

Layover in Madrid for 1h 15m

Tue Apr 1st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€365

8:20pm - 6:40pm
Mon Mar 31st 2025

29h 20m
Barcelona (BCN) → Panama (PTY)

2 Stops

Mon Mar 31st 2025 Vueling · VY 8464 Depart at 8:20pm from Barcelona (BCN) Fly for 2h 10m Arrive at 9:30pm in Lisbon (LIS)

Layover in Lisbon for 14h 5m

Tue Apr 1st 2025 Air Europa · UX 1150 Depart at 11:35am from Lisbon (LIS) Fly for 1h 15m Arrive at 1:50pm in Madrid (MAD)

Layover in Madrid for 1h 15m

Tue Apr 1st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€376.19

10:20pm - 6:40pm
Sun Mar 30th 2025

27h 20m
Valencia (VLC) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Ryanair · FR 1709 Depart at 10:20pm from Valencia (VLC) Fly for 1h 40m Arrive at 11:00pm in Porto (OPO)

Layover in Porto for 12h 35m

Mon Mar 31st 2025 Air Europa · UX 1146 Depart at 11:35am from Porto (OPO) Fly for 1h 10m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€379

8:25pm - 6:40pm
Mon Mar 31st 2025

29h 15m
Barcelona (BCN) → Panama (PTY)

2 Stops

Mon Mar 31st 2025 Vueling · VY 8480 Depart at 8:25pm from Barcelona (BCN) Fly for 1h 55m Arrive at 9:20pm in Porto (OPO)

Layover in Porto for 14h 15m

Tue Apr 1st 2025 Air Europa · UX 1146 Depart at 11:35am from Porto (OPO) Fly for 1h 10m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Tue Apr 1st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€387

5:55am - 6:40pm
Sun Mar 30th 2025

19h 45m
Valencia (VLC) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 TAP Portugal · TP 1097 Depart at 5:55am from Valencia (VLC) Fly for 1h 45m Arrive at 6:40am in Lisbon (LIS)

Layover in Lisbon for 4h 55m

Sun Mar 30th 2025 Air Europa · UX 1150 Depart at 11:35am from Lisbon (LIS) Fly for 1h 15m Arrive at 1:50pm in Madrid (MAD)

Layover in Madrid for 1h 15m

Sun Mar 30th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€392

3:05pm - 6:40pm
Sun Mar 30th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sun Mar 30th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€392

10:40pm - 6:40pm
Sun Mar 30th 2025

27h 0m
Barcelona (BCN) → Panama (PTY)

3 Stops

Sun Mar 30th 2025 TAP Portugal · TP 1039 Depart at 10:40pm from Barcelona (BCN) Fly for 2h 0m Arrive at 11:40pm in Lisbon (LIS)

Layover in Lisbon for 7h 15m

Mon Mar 31st 2025 TAP Portugal · TP 1920 Depart at 6:55am from Lisbon (LIS) Fly for 0h 55m Arrive at 7:50am in Porto (OPO)

Layover in Porto for 3h 45m

Mon Mar 31st 2025 Air Europa · UX 1146 Depart at 11:35am from Porto (OPO) Fly for 1h 10m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€394

12:25pm - 6:40pm
Mon Mar 31st 2025

13h 15m
Palma, Majorca (PMI) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Air Europa · UX 6048 Depart at 12:25pm from Palma, Majorca (PMI) Fly for 1h 25m Arrive at 1:50pm in Madrid (MAD)

Layover in Madrid for 1h 15m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€395

12:45pm - 6:40pm
Mon Mar 31st 2025

12h 55m
Bilbao (BIO) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Air Europa · UX 7158 Depart at 12:45pm from Bilbao (BIO) Fly for 1h 5m Arrive at 1:50pm in Madrid (MAD)

Layover in Madrid for 1h 15m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€396

3:05pm - 6:40pm
Mon Mar 31st 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€396

12:35pm - 6:40pm
Mon Mar 31st 2025

13h 5m
Valencia (VLC) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Air Europa · UX 4064 Depart at 12:35pm from Valencia (VLC) Fly for 0h 55m Arrive at 1:30pm in Madrid (MAD)

Layover in Madrid for 1h 35m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€396

12:35pm - 6:40pm
Sun Mar 30th 2025

13h 5m
Valencia (VLC) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Air Europa · UX 4064 Depart at 12:35pm from Valencia (VLC) Fly for 0h 55m Arrive at 1:30pm in Madrid (MAD)

Layover in Madrid for 1h 35m

Sun Mar 30th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€396

12:35pm - 6:40pm
Mon Mar 31st 2025

13h 5m
A Coruña (LCG) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Air Europa · UX 7234 Depart at 12:35pm from A Coruña (LCG) Fly for 1h 10m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€398

12:35pm - 6:40pm
Mon Mar 31st 2025

13h 5m
Málaga (AGP) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Air Europa · UX 5036 Depart at 12:35pm from Málaga (AGP) Fly for 1h 10m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€399

12:45pm - 6:40pm
Sun Mar 30th 2025

12h 55m
Bilbao (BIO) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Air Europa · UX 7158 Depart at 12:45pm from Bilbao (BIO) Fly for 1h 5m Arrive at 1:50pm in Madrid (MAD)

Layover in Madrid for 1h 15m

Sun Mar 30th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€405

11:50am - 6:40pm
Sun Mar 30th 2025

13h 50m
Barcelona (BCN) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Air Europa · UX 7706 Depart at 11:50am from Barcelona (BCN) Fly for 1h 30m Arrive at 1:20pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Sun Mar 30th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€405

11:50am - 6:40pm
Mon Mar 31st 2025

13h 50m
Barcelona (BCN) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Air Europa · UX 7706 Depart at 11:50am from Barcelona (BCN) Fly for 1h 30m Arrive at 1:20pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€407

8:35pm - 6:40pm
Sun Mar 30th 2025

29h 5m
Valencia (VLC) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Air Europa · UX 4060 Depart at 8:35pm from Valencia (VLC) Fly for 0h 55m Arrive at 9:30pm in Madrid (MAD)

Layover in Madrid for 17h 35m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€414

6:30am - 6:40pm
Mon Mar 31st 2025

19h 10m
Palma, Majorca (PMI) → Panama (PTY)

2 Stops

Mon Mar 31st 2025 Vueling · VY 8939 Depart at 6:30am from Palma, Majorca (PMI) Fly for 2h 5m Arrive at 8:35am in Paris (ORY)

Layover in Paris for 2h 20m

Mon Mar 31st 2025 Air Europa · UX 1028 Depart at 10:55am from Paris (ORY) Fly for 2h 0m Arrive at 12:55pm in Madrid (MAD)

Layover in Madrid for 2h 10m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€414

8:30pm - 6:40pm
Sun Mar 30th 2025

29h 10m
Barcelona (BCN) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Air Europa · UX 7708 Depart at 8:30pm from Barcelona (BCN) Fly for 1h 30m Arrive at 10:00pm in Madrid (MAD)

Layover in Madrid for 17h 5m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€415

8:30pm - 6:40pm
Mon Mar 31st 2025

29h 10m
Barcelona (BCN) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Air Europa · UX 7708 Depart at 8:30pm from Barcelona (BCN) Fly for 1h 30m Arrive at 10:00pm in Madrid (MAD)

Layover in Madrid for 17h 5m

Tue Apr 1st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€426

12:25pm - 6:40pm
Sun Mar 30th 2025

13h 15m
Palma, Majorca (PMI) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Air Europa · UX 6048 Depart at 12:25pm from Palma, Majorca (PMI) Fly for 1h 25m Arrive at 1:50pm in Madrid (MAD)

Layover in Madrid for 1h 15m

Sun Mar 30th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€431

7:10am - 6:40pm
Mon Mar 31st 2025

17h 30m
Tenerife (TFN) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Air Europa · UX 9045 Depart at 7:10am from Tenerife (TFN) Fly for 2h 45m Arrive at 10:55am in Madrid (MAD)

Layover in Madrid for 4h 10m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€434

6:10am - 6:40pm
Mon Mar 31st 2025

18h 30m
Las Palmas (LPA) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Air Europa · UX 9018 Depart at 6:10am from Las Palmas (LPA) Fly for 2h 45m Arrive at 9:55am in Madrid (MAD)

Layover in Madrid for 5h 10m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€435

10:00am - 6:40pm
Mon Mar 31st 2025

14h 40m
Las Palmas (LPA) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Air Europa · UX 9161 Depart at 10:00am from Las Palmas (LPA) Fly for 2h 45m Arrive at 1:45pm in Madrid (MAD)

Layover in Madrid for 1h 20m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€435

9:55am - 6:40pm
Mon Mar 31st 2025

14h 45m
Tenerife (TFN) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Air Europa · UX 9047 Depart at 9:55am from Tenerife (TFN) Fly for 2h 45m Arrive at 1:40pm in Madrid (MAD)

Layover in Madrid for 1h 25m

Mon Mar 31st 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€445

6:45am - 6:40pm
Sun Mar 30th 2025

18h 55m
Barcelona (BCN) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Vueling · VY 6400 Depart at 6:45am from Barcelona (BCN) Fly for 1h 50m Arrive at 8:35am in Venice (VCE)

Layover in Venice for 2h 10m

Sun Mar 30th 2025 Air Europa · UX 1082 Depart at 10:45am from Venice (VCE) Fly for 2h 40m Arrive at 1:25pm in Madrid (MAD)

Layover in Madrid for 1h 40m

Sun Mar 30th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€451

7:20am - 6:40pm
Sun Mar 30th 2025

18h 20m
Barcelona (BCN) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Vueling · VY 8460 Depart at 7:20am from Barcelona (BCN) Fly for 2h 10m Arrive at 8:30am in Lisbon (LIS)

Layover in Lisbon for 3h 5m

Sun Mar 30th 2025 Air Europa · UX 1150 Depart at 11:35am from Lisbon (LIS) Fly for 1h 15m Arrive at 1:50pm in Madrid (MAD)

Layover in Madrid for 1h 15m

Sun Mar 30th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
€495

5:30pm - 12:10am
Mon Mar 31st 2025

13h 40m
Madrid (MAD) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Avianca · AV 11 Depart at 5:30pm from Madrid (MAD) Fly for 10h 29m Arrive at 8:59pm in Bogotá (BOG)

Layover in Bogotá for 1h 26m

Mon Mar 31st 2025 Avianca · AV 40 Depart at 10:25pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:10am in Panama (PTY)

Book Flight
€495

5:30pm - 12:10am
Sun Mar 30th 2025

13h 40m
Madrid (MAD) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Avianca · AV 11 Depart at 5:30pm from Madrid (MAD) Fly for 10h 29m Arrive at 8:59pm in Bogotá (BOG)

Layover in Bogotá for 1h 26m

Sun Mar 30th 2025 Avianca · AV 40 Depart at 10:25pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:10am in Panama (PTY)

Book Flight
€495

9:40am - 4:30pm
Sun Mar 30th 2025

13h 50m
Madrid (MAD) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Avianca · AV 27 Depart at 9:40am from Madrid (MAD) Fly for 10h 30m Arrive at 1:10pm in Bogotá (BOG)

Layover in Bogotá for 1h 30m

Sun Mar 30th 2025 Avianca · AV 60 Depart at 2:40pm from Bogotá (BOG) Fly for 1h 50m Arrive at 4:30pm in Panama (PTY)

Book Flight
€495

9:40am - 4:30pm
Mon Mar 31st 2025

13h 50m
Madrid (MAD) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Avianca · AV 27 Depart at 9:40am from Madrid (MAD) Fly for 10h 30m Arrive at 1:10pm in Bogotá (BOG)

Layover in Bogotá for 1h 30m

Mon Mar 31st 2025 Avianca · AV 60 Depart at 2:40pm from Bogotá (BOG) Fly for 1h 50m Arrive at 4:30pm in Panama (PTY)

Book Flight
€495

12:30am - 10:10am
Sun Mar 30th 2025

15h 40m
Madrid (MAD) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Avianca · AV 47 Depart at 12:30am from Madrid (MAD) Fly for 10h 30m Arrive at 5:00am in Bogotá (BOG)

Layover in Bogotá for 3h 15m

Sun Mar 30th 2025 Avianca · AV 8380 Depart at 8:15am from Bogotá (BOG) Fly for 1h 55m Arrive at 10:10am in Panama (PTY)

Book Flight
€495

1:30am - 10:10am
Mon Mar 31st 2025

15h 40m
Madrid (MAD) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Avianca · AV 47 Depart at 1:30am from Madrid (MAD) Fly for 10h 30m Arrive at 5:00am in Bogotá (BOG)

Layover in Bogotá for 3h 15m

Mon Mar 31st 2025 Avianca · AV 8380 Depart at 8:15am from Bogotá (BOG) Fly for 1h 55m Arrive at 10:10am in Panama (PTY)

Book Flight
€503

6:30pm - 4:26pm
Mon Mar 31st 2025

28h 56m
Barcelona (BCN) → Panama (PTY)

2 Stops

Mon Mar 31st 2025 Vueling · VY 9795 Depart at 6:30pm from Barcelona (BCN) Fly for 8h 35m Arrive at 9:05pm in Boston (BOS)

Layover in Boston for 11h 15m

Tue Apr 1st 2025 Spirit Airlines · NK 183 Depart at 8:20am from Boston (BOS) Fly for 3h 41m Arrive at 12:01pm in Miami (MIA)

Layover in Miami for 2h 15m

Tue Apr 1st 2025 Copa Airlines · CM 481 Depart at 2:16pm from Miami (MIA) Fly for 3h 10m Arrive at 4:26pm in Panama (PTY)

Book Flight
€523

2:00pm - 9:10pm
Sun Mar 30th 2025

14h 10m
Barcelona (BCN) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Avianca · AV 19 Depart at 2:00pm from Barcelona (BCN) Fly for 11h 10m Arrive at 6:10pm in Bogotá (BOG)

Layover in Bogotá for 1h 15m

Sun Mar 30th 2025 Avianca · AV 56 Depart at 7:25pm from Bogotá (BOG) Fly for 1h 45m Arrive at 9:10pm in Panama (PTY)

Book Flight
€523

2:00pm - 12:10am
Sun Mar 30th 2025

17h 10m
Barcelona (BCN) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Avianca · AV 19 Depart at 2:00pm from Barcelona (BCN) Fly for 11h 10m Arrive at 6:10pm in Bogotá (BOG)

Layover in Bogotá for 4h 15m

Sun Mar 30th 2025 Avianca · AV 40 Depart at 10:25pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:10am in Panama (PTY)

Book Flight
€524

3:25pm - 7:30am
Sun Mar 30th 2025

23h 5m
Madrid (MAD) → Panama (BLB)

1 Stop

Sun Mar 30th 2025 Air Europa · UX 199 Depart at 3:25pm from Madrid (MAD) Fly for 10h 10m Arrive at 6:35pm in Medellín (MDE)

Layover in Medellín for 11h 35m

Mon Mar 31st 2025 Wingo airlines · P5 7042 Depart at 6:10am from Medellín (MDE) Fly for 1h 20m Arrive at 7:30am in Panama (BLB)

Book Flight
€564

2:20pm - 8:00am
Mon Mar 31st 2025

24h 40m
Palma, Majorca (PMI) → Panama (BLB)

2 Stops

Mon Mar 31st 2025 Avianca · AV 6190 Depart at 2:20pm from Palma, Majorca (PMI) Fly for 1h 25m Arrive at 3:45pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Mon Mar 31st 2025 Avianca · AV 11 Depart at 5:30pm from Madrid (MAD) Fly for 10h 29m Arrive at 8:59pm in Bogotá (BOG)

Layover in Bogotá for 9h 16m

Tue Apr 1st 2025 Wingo airlines · P5 7068 Depart at 6:15am from Bogotá (BOG) Fly for 1h 45m Arrive at 8:00am in Panama (BLB)

Book Flight
€568

1:30pm - 8:00am
Mon Mar 31st 2025

25h 30m
Bilbao (BIO) → Panama (BLB)

2 Stops

Mon Mar 31st 2025 Avianca · AV 6175 Depart at 1:30pm from Bilbao (BIO) Fly for 1h 10m Arrive at 2:40pm in Madrid (MAD)

Layover in Madrid for 2h 50m

Mon Mar 31st 2025 Avianca · AV 11 Depart at 5:30pm from Madrid (MAD) Fly for 10h 29m Arrive at 8:59pm in Bogotá (BOG)

Layover in Bogotá for 9h 16m

Tue Apr 1st 2025 Wingo airlines · P5 7068 Depart at 6:15am from Bogotá (BOG) Fly for 1h 45m Arrive at 8:00am in Panama (BLB)

Book Flight
€569

9:45pm - 4:30pm
Mon Mar 31st 2025

25h 45m
Madrid (MAD) → Panama (PTY)

2 Stops

Mon Mar 31st 2025 Iberia Airlines · IB 591 Depart at 9:45pm from Madrid (MAD) Fly for 2h 5m Arrive at 11:50pm in Paris (CDG)

Layover in Paris for 8h 55m

Tue Apr 1st 2025 Avianca · AV 229 Depart at 8:45am from Paris (CDG) Fly for 11h 14m Arrive at 12:59pm in Bogotá (BOG)

Layover in Bogotá for 1h 41m

Tue Apr 1st 2025 Avianca · AV 60 Depart at 2:40pm from Bogotá (BOG) Fly for 1h 50m Arrive at 4:30pm in Panama (PTY)

Book Flight
€580

1:45pm - 11:20am
Sun Mar 30th 2025

28h 35m
Barcelona (BCN) → Penonomé (RIH)

2 Stops

Sun Mar 30th 2025 Royal Air Maroc · AT 965 Depart at 1:45pm from Barcelona (BCN) Fly for 3h 15m Arrive at 3:00pm in Casablanca (CMN)

Layover in Casablanca for 1h 45m

Sun Mar 30th 2025 Royal Air Maroc · AT 210 Depart at 4:45pm from Casablanca (CMN) Fly for 7h 25m Arrive at 8:10pm in Toronto (YYZ)

Layover in Toronto for 10h 20m

Mon Mar 31st 2025 Air Transat · TS 346 Depart at 6:30am from Toronto (YYZ) Fly for 5h 50m Arrive at 11:20am in Penonomé (RIH)

Book Flight
€589

10:05am - 5:55pm
Sun Mar 30th 2025

14h 50m
Madrid (MAD) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Air France · AF 1001 Depart at 10:05am from Madrid (MAD) Fly for 2h 5m Arrive at 12:10pm in Paris (CDG)

Layover in Paris for 1h 50m

Sun Mar 30th 2025 Air France · AF 474 Depart at 2:00pm from Paris (CDG) Fly for 10h 55m Arrive at 5:55pm in Panama (PTY)

Book Flight
€589

8:25pm - 4:50pm
Sun Mar 30th 2025

27h 25m
Madrid (MAD) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 KLM Royal Dutch Airlines · KL 1508 Depart at 8:25pm from Madrid (MAD) Fly for 2h 35m Arrive at 11:00pm in Amsterdam (AMS)

Layover in Amsterdam for 13h 55m

Mon Mar 31st 2025 KLM Royal Dutch Airlines · KL 757 Depart at 12:55pm from Amsterdam (AMS) Fly for 10h 55m Arrive at 4:50pm in Panama (PTY)

Book Flight
€594

3:35am - 10:27am
Mon Mar 31st 2025

13h 52m
Madrid (MAD) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Air Europa · UX 39 Depart at 3:35am from Madrid (MAD) Fly for 10h 55m Arrive at 7:30am in Quito (UIO)

Layover in Quito for 1h 0m

Mon Mar 31st 2025 Copa Airlines · CM 336 Depart at 8:30am from Quito (UIO) Fly for 1h 57m Arrive at 10:27am in Panama (PTY)

Book Flight
€594

3:15pm - 8:00am
Mon Mar 31st 2025

23h 45m
Madrid (MAD) → Panama (BLB)

1 Stop

Mon Mar 31st 2025 Air Europa · UX 193 Depart at 3:15pm from Madrid (MAD) Fly for 10h 0m Arrive at 6:15pm in Bogotá (BOG)

Layover in Bogotá for 12h 0m

Tue Apr 1st 2025 Wingo airlines · P5 7068 Depart at 6:15am from Bogotá (BOG) Fly for 1h 45m Arrive at 8:00am in Panama (BLB)

Book Flight
€598

5:30pm - 8:00am
Mon Mar 31st 2025

21h 30m
Madrid (MAD) → Panama (BLB)

1 Stop

Mon Mar 31st 2025 Avianca · AV 11 Depart at 5:30pm from Madrid (MAD) Fly for 10h 29m Arrive at 8:59pm in Bogotá (BOG)

Layover in Bogotá for 9h 16m

Tue Apr 1st 2025 Wingo airlines · P5 7068 Depart at 6:15am from Bogotá (BOG) Fly for 1h 45m Arrive at 8:00am in Panama (BLB)

Book Flight
€599

9:30pm - 8:55am
Mon Mar 31st 2025

18h 25m
Donostia / San Sebastián (EAS) → Panama (PTY)

2 Stops

Mon Mar 31st 2025 Avianca · AV 6181 Depart at 9:30pm from Donostia / San Sebastián (EAS) Fly for 1h 10m Arrive at 10:40pm in Madrid (MAD)

Layover in Madrid for 2h 50m

Tue Apr 1st 2025 Avianca · AV 47 Depart at 1:30am from Madrid (MAD) Fly for 10h 30m Arrive at 5:00am in Bogotá (BOG)

Layover in Bogotá for 2h 10m

Tue Apr 1st 2025 Avianca · AV 58 Depart at 7:10am from Bogotá (BOG) Fly for 1h 45m Arrive at 8:55am in Panama (PTY)

Book Flight
€599

6:15am - 8:08pm
Sun Mar 30th 2025

20h 53m
Valencia (VLC) → Panama (BLB)

3 Stops

Sun Mar 30th 2025 Avianca · AV 6176 Depart at 6:15am from Valencia (VLC) Fly for 1h 5m Arrive at 7:20am in Madrid (MAD)

Layover in Madrid for 2h 20m

Sun Mar 30th 2025 Avianca · AV 27 Depart at 9:40am from Madrid (MAD) Fly for 10h 30m Arrive at 1:10pm in Bogotá (BOG)

Layover in Bogotá for 2h 20m

Sun Mar 30th 2025 JetSMART · JA 5124 Depart at 3:30pm from Bogotá (BOG) Fly for 1h 5m Arrive at 4:35pm in Medellín (MDE)

Layover in Medellín for 2h 13m

Sun Mar 30th 2025 Wingo airlines · P5 7048 Depart at 6:48pm from Medellín (MDE) Fly for 1h 20m Arrive at 8:08pm in Panama (BLB)

Book Flight
€600

2:55pm - 8:00am
Mon Mar 31st 2025

24h 5m
Madrid (MAD) → Panama (BLB)

1 Stop

Mon Mar 31st 2025 Plus Ultra Lineas Aereas · PU 221 Depart at 2:55pm from Madrid (MAD) Fly for 10h 30m Arrive at 6:25pm in Bogotá (BOG)

Layover in Bogotá for 11h 50m

Tue Apr 1st 2025 Wingo airlines · P5 7068 Depart at 6:15am from Bogotá (BOG) Fly for 1h 45m Arrive at 8:00am in Panama (BLB)

Book Flight
€601

2:00pm - 7:30am
Mon Mar 31st 2025

24h 30m
Barcelona (BCN) → Panama (BLB)

2 Stops

Mon Mar 31st 2025 Avianca · AV 19 Depart at 2:00pm from Barcelona (BCN) Fly for 11h 10m Arrive at 6:10pm in Bogotá (BOG)

Layover in Bogotá for 2h 25m

Mon Mar 31st 2025 Avianca · AV 9312 Depart at 8:35pm from Bogotá (BOG) Fly for 0h 57m Arrive at 9:32pm in Medellín (MDE)

Layover in Medellín for 8h 38m

Tue Apr 1st 2025 Wingo airlines · P5 7042 Depart at 6:10am from Medellín (MDE) Fly for 1h 20m Arrive at 7:30am in Panama (BLB)

Book Flight
€602

9:35pm - 8:55am
Mon Mar 31st 2025

18h 20m
Bilbao (BIO) → Panama (PTY)

2 Stops

Mon Mar 31st 2025 Avianca · AV 6161 Depart at 9:35pm from Bilbao (BIO) Fly for 1h 10m Arrive at 10:45pm in Madrid (MAD)

Layover in Madrid for 2h 45m

Tue Apr 1st 2025 Avianca · AV 47 Depart at 1:30am from Madrid (MAD) Fly for 10h 30m Arrive at 5:00am in Bogotá (BOG)

Layover in Bogotá for 2h 10m

Tue Apr 1st 2025 Avianca · AV 58 Depart at 7:10am from Bogotá (BOG) Fly for 1h 45m Arrive at 8:55am in Panama (PTY)

Book Flight
€603

3:15pm - 7:30am
Mon Mar 31st 2025

23h 15m
Madrid (MAD) → Panama (BLB)

2 Stops

Mon Mar 31st 2025 Air Europa · UX 193 Depart at 3:15pm from Madrid (MAD) Fly for 10h 0m Arrive at 6:15pm in Bogotá (BOG)

Layover in Bogotá for 2h 45m

Mon Mar 31st 2025 JetSMART · JA 5118 Depart at 9:00pm from Bogotá (BOG) Fly for 1h 5m Arrive at 10:05pm in Medellín (MDE)

Layover in Medellín for 8h 5m

Tue Apr 1st 2025 Wingo airlines · P5 7042 Depart at 6:10am from Medellín (MDE) Fly for 1h 20m Arrive at 7:30am in Panama (BLB)

Book Flight
€609

1:30am - 12:36pm
Mon Mar 31st 2025

18h 6m
Madrid (MAD) → Panama (BLB)

2 Stops

Mon Mar 31st 2025 Avianca · AV 47 Depart at 1:30am from Madrid (MAD) Fly for 10h 30m Arrive at 5:00am in Bogotá (BOG)

Layover in Bogotá for 2h 19m

Mon Mar 31st 2025 Wingo airlines · P5 7250 Depart at 7:19am from Bogotá (BOG) Fly for 1h 9m Arrive at 8:28am in Cali (CLO)

Layover in Cali for 2h 46m

Mon Mar 31st 2025 Wingo airlines · P5 7038 Depart at 11:14am from Cali (CLO) Fly for 1h 22m Arrive at 12:36pm in Panama (BLB)

Book Flight
€609

6:15am - 8:08pm
Sun Mar 30th 2025

20h 53m
Valencia (VLC) → Panama (BLB)

3 Stops

Sun Mar 30th 2025 Avianca · AV 6176 Depart at 6:15am from Valencia (VLC) Fly for 1h 5m Arrive at 7:20am in Madrid (MAD)

Layover in Madrid for 2h 20m

Sun Mar 30th 2025 Avianca · AV 27 Depart at 9:40am from Madrid (MAD) Fly for 10h 30m Arrive at 1:10pm in Bogotá (BOG)

Layover in Bogotá for 2h 35m

Sun Mar 30th 2025 Avianca · AV 9324 Depart at 3:45pm from Bogotá (BOG) Fly for 1h 0m Arrive at 4:45pm in Medellín (MDE)

Layover in Medellín for 2h 3m

Sun Mar 30th 2025 Wingo airlines · P5 7048 Depart at 6:48pm from Medellín (MDE) Fly for 1h 20m Arrive at 8:08pm in Panama (BLB)

Book Flight
€609

2:55pm - 7:30am
Mon Mar 31st 2025

23h 35m
Madrid (MAD) → Panama (BLB)

2 Stops

Mon Mar 31st 2025 Plus Ultra Lineas Aereas · PU 221 Depart at 2:55pm from Madrid (MAD) Fly for 10h 30m Arrive at 6:25pm in Bogotá (BOG)

Layover in Bogotá for 2h 35m

Mon Mar 31st 2025 JetSMART · JA 5118 Depart at 9:00pm from Bogotá (BOG) Fly for 1h 5m Arrive at 10:05pm in Medellín (MDE)

Layover in Medellín for 8h 5m

Tue Apr 1st 2025 Wingo airlines · P5 7042 Depart at 6:10am from Medellín (MDE) Fly for 1h 20m Arrive at 7:30am in Panama (BLB)

Book Flight
€609

12:30am - 8:08pm
Sun Mar 30th 2025

25h 38m
Madrid (MAD) → Panama (BLB)

2 Stops

Sun Mar 30th 2025 Avianca · AV 47 Depart at 12:30am from Madrid (MAD) Fly for 10h 30m Arrive at 5:00am in Bogotá (BOG)

Layover in Bogotá for 2h 0m

Sun Mar 30th 2025 JetSMART · JA 5110 Depart at 7:00am from Bogotá (BOG) Fly for 1h 5m Arrive at 8:05am in Medellín (MDE)

Layover in Medellín for 10h 43m

Sun Mar 30th 2025 Wingo airlines · P5 7048 Depart at 6:48pm from Medellín (MDE) Fly for 1h 20m Arrive at 8:08pm in Panama (BLB)

Book Flight
€609

5:30pm - 12:36pm
Sun Mar 30th 2025

26h 6m
Madrid (MAD) → Panama (BLB)

2 Stops

Sun Mar 30th 2025 Avianca · AV 11 Depart at 5:30pm from Madrid (MAD) Fly for 10h 29m Arrive at 8:59pm in Bogotá (BOG)

Layover in Bogotá for 10h 20m

Mon Mar 31st 2025 Wingo airlines · P5 7250 Depart at 7:19am from Bogotá (BOG) Fly for 1h 9m Arrive at 8:28am in Cali (CLO)

Layover in Cali for 2h 46m

Mon Mar 31st 2025 Wingo airlines · P5 7038 Depart at 11:14am from Cali (CLO) Fly for 1h 22m Arrive at 12:36pm in Panama (BLB)

Book Flight
€610

7:00am - 8:15pm
Sun Mar 30th 2025

20h 15m
Barcelona (BCN) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Iberia Airlines · IB 426 Depart at 7:00am from Barcelona (BCN) Fly for 1h 25m Arrive at 8:25am in Madrid (MAD)

Layover in Madrid for 3h 5m

Sun Mar 30th 2025 Iberia Airlines · IB 243 Depart at 11:30am from Madrid (MAD) Fly for 11h 35m Arrive at 3:05pm in San José (SJO)

Layover in San José for 2h 46m

Sun Mar 30th 2025 Iberia Airlines · IB 7730 Depart at 5:51pm from San José (SJO) Fly for 1h 24m Arrive at 8:15pm in Panama (PTY)

Book Flight
€610

7:00am - 8:30pm
Sun Mar 30th 2025

20h 30m
Barcelona (BCN) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Iberia Airlines · IB 426 Depart at 7:00am from Barcelona (BCN) Fly for 1h 25m Arrive at 8:25am in Madrid (MAD)

Layover in Madrid for 3h 5m

Sun Mar 30th 2025 Iberia Airlines · IB 243 Depart at 11:30am from Madrid (MAD) Fly for 11h 35m Arrive at 3:05pm in San José (SJO)

Layover in San José for 3h 1m

Sun Mar 30th 2025 Iberia Airlines · IB 7769 Depart at 6:06pm from San José (SJO) Fly for 1h 24m Arrive at 8:30pm in Panama (PTY)

Book Flight
€610

5:30pm - 12:36pm
Sun Mar 30th 2025

26h 6m
Madrid (MAD) → Panama (BLB)

2 Stops

Sun Mar 30th 2025 Avianca · AV 11 Depart at 5:30pm from Madrid (MAD) Fly for 10h 29m Arrive at 8:59pm in Bogotá (BOG)

Layover in Bogotá for 8h 11m

Mon Mar 31st 2025 Avianca · AV 8409 Depart at 5:10am from Bogotá (BOG) Fly for 1h 1m Arrive at 6:11am in Cali (CLO)

Layover in Cali for 5h 3m

Mon Mar 31st 2025 Wingo airlines · P5 7038 Depart at 11:14am from Cali (CLO) Fly for 1h 22m Arrive at 12:36pm in Panama (BLB)

Book Flight
€614

3:35am - 2:27pm
Mon Mar 31st 2025

17h 52m
Madrid (MAD) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Air Europa · UX 39 Depart at 3:35am from Madrid (MAD) Fly for 13h 20m Arrive at 9:55am in Guayaquil (GYE)

Layover in Guayaquil for 2h 21m

Mon Mar 31st 2025 Copa Airlines · CM 377 Depart at 12:16pm from Guayaquil (GYE) Fly for 2h 11m Arrive at 2:27pm in Panama (PTY)

Book Flight
€615

5:00pm - 7:30am
Sun Mar 30th 2025

21h 30m
Madrid (MAD) → Panama (BLB)

1 Stop

Sun Mar 30th 2025 Avianca · AV 17 Depart at 5:00pm from Madrid (MAD) Fly for 10h 35m Arrive at 8:35pm in Medellín (MDE)

Layover in Medellín for 9h 35m

Mon Mar 31st 2025 Wingo airlines · P5 7042 Depart at 6:10am from Medellín (MDE) Fly for 1h 20m Arrive at 7:30am in Panama (BLB)

Book Flight
€615

5:00pm - 7:30am
Mon Mar 31st 2025

21h 30m
Madrid (MAD) → Panama (BLB)

1 Stop

Mon Mar 31st 2025 Avianca · AV 17 Depart at 5:00pm from Madrid (MAD) Fly for 10h 35m Arrive at 8:35pm in Medellín (MDE)

Layover in Medellín for 9h 35m

Tue Apr 1st 2025 Wingo airlines · P5 7042 Depart at 6:10am from Medellín (MDE) Fly for 1h 20m Arrive at 7:30am in Panama (BLB)

Book Flight
€616

9:30am - 4:50pm
Sun Mar 30th 2025

14h 20m
Barcelona (BCN) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 KLM Royal Dutch Airlines · KL 1498 Depart at 9:30am from Barcelona (BCN) Fly for 2h 20m Arrive at 11:50am in Amsterdam (AMS)

Layover in Amsterdam for 1h 5m

Sun Mar 30th 2025 KLM Royal Dutch Airlines · KL 757 Depart at 12:55pm from Amsterdam (AMS) Fly for 10h 55m Arrive at 4:50pm in Panama (PTY)

Book Flight
€616

9:55am - 5:55pm
Sun Mar 30th 2025

15h 0m
Barcelona (BCN) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Air France · AF 1149 Depart at 9:55am from Barcelona (BCN) Fly for 1h 55m Arrive at 11:50am in Paris (CDG)

Layover in Paris for 2h 10m

Sun Mar 30th 2025 Air France · AF 474 Depart at 2:00pm from Paris (CDG) Fly for 10h 55m Arrive at 5:55pm in Panama (PTY)

Book Flight
€616

6:20am - 4:50pm
Sun Mar 30th 2025

17h 30m
Barcelona (BCN) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 KLM Royal Dutch Airlines · KL 1510 Depart at 6:20am from Barcelona (BCN) Fly for 2h 20m Arrive at 8:40am in Amsterdam (AMS)

Layover in Amsterdam for 4h 15m

Sun Mar 30th 2025 KLM Royal Dutch Airlines · KL 757 Depart at 12:55pm from Amsterdam (AMS) Fly for 10h 55m Arrive at 4:50pm in Panama (PTY)

Book Flight
€616

6:10am - 5:55pm
Sun Mar 30th 2025

18h 45m
Barcelona (BCN) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Air France · AF 1449 Depart at 6:10am from Barcelona (BCN) Fly for 1h 55m Arrive at 8:05am in Paris (CDG)

Layover in Paris for 5h 55m

Sun Mar 30th 2025 Air France · AF 474 Depart at 2:00pm from Paris (CDG) Fly for 10h 55m Arrive at 5:55pm in Panama (PTY)

Book Flight
€616

9:05pm - 2:27pm
Sun Mar 30th 2025

24h 22m
Bilbao (BIO) → Panama (PTY)

3 Stops

Sun Mar 30th 2025 Air Europa · UX 7160 Depart at 9:05pm from Bilbao (BIO) Fly for 1h 5m Arrive at 10:10pm in Madrid (MAD)

Layover in Madrid for 5h 25m

Mon Mar 31st 2025 Air Europa · UX 39 Depart at 3:35am from Madrid (MAD) Fly for 10h 55m Arrive at 7:30am in Quito (UIO)

Layover in Quito for 1h 25m

Mon Mar 31st 2025 Air Europa · UX 39 Depart at 8:55am from Quito (UIO) Fly for 1h 0m Arrive at 9:55am in Guayaquil (GYE)

Layover in Guayaquil for 2h 21m

Mon Mar 31st 2025 Copa Airlines · CM 377 Depart at 12:16pm from Guayaquil (GYE) Fly for 2h 11m Arrive at 2:27pm in Panama (PTY)

Book Flight
€616

7:40pm - 4:50pm
Sun Mar 30th 2025

28h 10m
Barcelona (BCN) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 KLM Royal Dutch Airlines · KL 1520 Depart at 7:40pm from Barcelona (BCN) Fly for 2h 15m Arrive at 9:55pm in Amsterdam (AMS)

Layover in Amsterdam for 15h 0m

Mon Mar 31st 2025 KLM Royal Dutch Airlines · KL 757 Depart at 12:55pm from Amsterdam (AMS) Fly for 10h 55m Arrive at 4:50pm in Panama (PTY)

Book Flight
€617

8:45am - 4:05pm
Mon Mar 31st 2025

14h 20m
Barcelona (BCN) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Iberia Airlines · IB 402 Depart at 8:45am from Barcelona (BCN) Fly for 1h 25m Arrive at 10:10am in Madrid (MAD)

Layover in Madrid for 1h 50m

Mon Mar 31st 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 11h 5m Arrive at 4:05pm in Panama (PTY)

Book Flight
€618

8:55am - 4:50pm
Mon Mar 31st 2025

14h 55m
Barcelona (BCN) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 KLM Royal Dutch Airlines · KL 2678 Depart at 8:55am from Barcelona (BCN) Fly for 2h 25m Arrive at 11:20am in Amsterdam (AMS)

Layover in Amsterdam for 1h 35m

Mon Mar 31st 2025 KLM Royal Dutch Airlines · KL 757 Depart at 12:55pm from Amsterdam (AMS) Fly for 10h 55m Arrive at 4:50pm in Panama (PTY)

Book Flight
€620

12:30am - 8:08pm
Sun Mar 30th 2025

25h 38m
Madrid (MAD) → Panama (BLB)

2 Stops

Sun Mar 30th 2025 Avianca · AV 47 Depart at 12:30am from Madrid (MAD) Fly for 10h 30m Arrive at 5:00am in Bogotá (BOG)

Layover in Bogotá for 3h 0m

Sun Mar 30th 2025 Wingo airlines · P5 7270 Depart at 8:00am from Bogotá (BOG) Fly for 1h 2m Arrive at 9:02am in Medellín (MDE)

Layover in Medellín for 9h 46m

Sun Mar 30th 2025 Wingo airlines · P5 7048 Depart at 6:48pm from Medellín (MDE) Fly for 1h 20m Arrive at 8:08pm in Panama (BLB)

Book Flight
€621

9:15am - 4:05pm
Mon Mar 31st 2025

13h 50m
Barcelona (BCN) → Panama (PTY)

1 Stop

Mon Mar 31st 2025 Iberia Airlines · IB 404 Depart at 9:15am from Barcelona (BCN) Fly for 1h 25m Arrive at 10:40am in Madrid (MAD)

Layover in Madrid for 1h 20m

Mon Mar 31st 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 11h 5m Arrive at 4:05pm in Panama (PTY)

Book Flight
€621

9:40am - 8:08pm
Sun Mar 30th 2025

17h 28m
Madrid (MAD) → Panama (BLB)

2 Stops

Sun Mar 30th 2025 Avianca · AV 27 Depart at 9:40am from Madrid (MAD) Fly for 10h 30m Arrive at 1:10pm in Bogotá (BOG)

Layover in Bogotá for 1h 10m

Sun Mar 30th 2025 Avianca · AV 9306 Depart at 2:20pm from Bogotá (BOG) Fly for 0h 57m Arrive at 3:17pm in Medellín (MDE)

Layover in Medellín for 3h 31m

Sun Mar 30th 2025 Wingo airlines · P5 7048 Depart at 6:48pm from Medellín (MDE) Fly for 1h 20m Arrive at 8:08pm in Panama (BLB)

Book Flight
€621

9:40pm - 8:55am
Mon Mar 31st 2025

18h 15m
A Coruña (LCG) → Panama (PTY)

2 Stops

Mon Mar 31st 2025 Iberia Airlines · IB 1118 Depart at 9:40pm from A Coruña (LCG) Fly for 1h 20m Arrive at 11:00pm in Madrid (MAD)

Layover in Madrid for 2h 30m

Tue Apr 1st 2025 Avianca · AV 47 Depart at 1:30am from Madrid (MAD) Fly for 10h 30m Arrive at 5:00am in Bogotá (BOG)

Layover in Bogotá for 2h 10m

Tue Apr 1st 2025 Avianca · AV 58 Depart at 7:10am from Bogotá (BOG) Fly for 1h 45m Arrive at 8:55am in Panama (PTY)

Book Flight
€621

5:30pm - 7:30am
Sun Mar 30th 2025

21h 0m
Madrid (MAD) → Panama (BLB)

2 Stops

Sun Mar 30th 2025 Avianca · AV 11 Depart at 5:30pm from Madrid (MAD) Fly for 10h 29m Arrive at 8:59pm in Bogotá (BOG)

Layover in Bogotá for 1h 41m

Sun Mar 30th 2025 Avianca · AV 9342 Depart at 10:40pm from Bogotá (BOG) Fly for 1h 2m Arrive at 11:42pm in Medellín (MDE)

Layover in Medellín for 6h 28m

Mon Mar 31st 2025 Wingo airlines · P5 7042 Depart at 6:10am from Medellín (MDE) Fly for 1h 20m Arrive at 7:30am in Panama (BLB)

Book Flight
€621

5:30pm - 7:30am
Mon Mar 31st 2025

21h 0m
Madrid (MAD) → Panama (BLB)

2 Stops

Mon Mar 31st 2025 Avianca · AV 11 Depart at 5:30pm from Madrid (MAD) Fly for 10h 29m Arrive at 8:59pm in Bogotá (BOG)

Layover in Bogotá for 1h 41m

Mon Mar 31st 2025 Avianca · AV 9342 Depart at 10:40pm from Bogotá (BOG) Fly for 1h 2m Arrive at 11:42pm in Medellín (MDE)

Layover in Medellín for 6h 28m

Tue Apr 1st 2025 Wingo airlines · P5 7042 Depart at 6:10am from Medellín (MDE) Fly for 1h 20m Arrive at 7:30am in Panama (BLB)

Book Flight
€623

2:55pm - 7:30am
Mon Mar 31st 2025

23h 35m
Madrid (MAD) → Panama (BLB)

2 Stops

Mon Mar 31st 2025 Plus Ultra Lineas Aereas · PU 221 Depart at 2:55pm from Madrid (MAD) Fly for 10h 30m Arrive at 6:25pm in Bogotá (BOG)

Layover in Bogotá for 2h 10m

Mon Mar 31st 2025 Avianca · AV 9312 Depart at 8:35pm from Bogotá (BOG) Fly for 0h 57m Arrive at 9:32pm in Medellín (MDE)

Layover in Medellín for 8h 38m

Tue Apr 1st 2025 Wingo airlines · P5 7042 Depart at 6:10am from Medellín (MDE) Fly for 1h 20m Arrive at 7:30am in Panama (BLB)

Book Flight
€626

1:30am - 12:36pm
Mon Mar 31st 2025

18h 6m
Madrid (MAD) → Panama (BLB)

2 Stops

Mon Mar 31st 2025 Avianca · AV 47 Depart at 1:30am from Madrid (MAD) Fly for 10h 30m Arrive at 5:00am in Bogotá (BOG)

Layover in Bogotá for 1h 29m

Mon Mar 31st 2025 Avianca · AV 9694 Depart at 6:29am from Bogotá (BOG) Fly for 1h 6m Arrive at 7:35am in Cali (CLO)

Layover in Cali for 3h 39m

Mon Mar 31st 2025 Wingo airlines · P5 7038 Depart at 11:14am from Cali (CLO) Fly for 1h 22m Arrive at 12:36pm in Panama (BLB)

Book Flight
€626

9:10pm - 4:05pm
Sun Mar 30th 2025

25h 55m
Barcelona (BCN) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Iberia Airlines · IB 424 Depart at 9:10pm from Barcelona (BCN) Fly for 1h 25m Arrive at 10:35pm in Madrid (MAD)

Layover in Madrid for 13h 25m

Mon Mar 31st 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 11h 5m Arrive at 4:05pm in Panama (PTY)

Book Flight
€626

7:55pm - 4:05pm
Sun Mar 30th 2025

27h 10m
Barcelona (BCN) → Panama (PTY)

1 Stop

Sun Mar 30th 2025 Iberia Airlines · IB 422 Depart at 7:55pm from Barcelona (BCN) Fly for 1h 25m Arrive at 9:20pm in Madrid (MAD)

Layover in Madrid for 14h 40m

Mon Mar 31st 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 11h 5m Arrive at 4:05pm in Panama (PTY)

Book Flight
€636

12:00pm - 4:05pm
Mon Mar 31st 2025

11h 5m
Madrid (MAD) → Panama (PTY)

Direct

Mon Mar 31st 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 11h 5m Arrive at 4:05pm in Panama (PTY)

Book Flight
€649

9:10pm - 8:00am
Mon Mar 31st 2025

17h 50m
Barcelona (BCN) → Panama (BLB)

2 Stops

Mon Mar 31st 2025 Iberia Airlines · IB 424 Depart at 9:10pm from Barcelona (BCN) Fly for 1h 25m Arrive at 10:35pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Tue Apr 1st 2025 Iberia Airlines · IB 155 Depart at 12:30am from Madrid (MAD) Fly for 10h 30m Arrive at 4:00am in Bogotá (BOG)

Layover in Bogotá for 2h 15m

Tue Apr 1st 2025 Wingo airlines · P5 7068 Depart at 6:15am from Bogotá (BOG) Fly for 1h 45m Arrive at 8:00am in Panama (BLB)

Book Flight
€676

9:50pm - 10:10am
Sun Mar 30th 2025

19h 20m
Seville (SVQ) → Panama (PTY)

2 Stops

Sun Mar 30th 2025 Avianca · AV 6057 Depart at 9:50pm from Seville (SVQ) Fly for 1h 5m Arrive at 10:55pm in Madrid (MAD)

Layover in Madrid for 2h 35m

Mon Mar 31st 2025 Avianca · AV 47 Depart at 1:30am from Madrid (MAD) Fly for 10h 30m Arrive at 5:00am in Bogotá (BOG)

Layover in Bogotá for 3h 15m

Mon Mar 31st 2025 Avianca · AV 8380 Depart at 8:15am from Bogotá (BOG) Fly for 1h 55m Arrive at 10:10am in Panama (PTY)

Book Flight

Sarah Belizaire

@sarahbb1

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John Ford

@eyupitsjohn

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Roaming Sonaa

@roamingsonaa

For people wanting to maximize their trips, Flightlist is my newest travel hack for uncovering the coolest routes at irresistible prices. No stress, no annoying ads — just seamless flight booking with amazing functionality. It's designed for remote workers, backpackers, and people living abroad.

Read Sonaa's 7 Amazing Skyscanner Alternatives for Booking Travel

ANDY TRAVELS

@andy_travels

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Travel With Bender

@travelwitbender

Did you spot my recent article about how to score cheap one way flights? ✈️ FlightList is my new secret tool for discovering cheap routes, within a departure date range. Plus you can also search by country/region for departures & destinations. Powerful! 💪

Read Josh's Ultimate Guide To Find Cheap One Way Flights

Wesley Mergard

@travel.with.wes

One useful tool I've found for evaluating different departure and return dates is called FlightList.io. You can quickly scan different travel date ranges, carriers and one way flight options to easily determine the cheapest flight combinations for your trip.

Read Wesley's My Best Cheap Flight Hacks (Why Pay More?)

Cheap Flights from Spain to Panama (ES to PA)

Sarah Belizaire

John Ford

Roaming Sonaa

ANDY TRAVELS

Travel With Bender

Wesley Mergard

Latest Cheap Flight Searches

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Why I Built FlightList & Solved My Own Problem

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